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A9AZ72 (AROA_HERA2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Haur_0970
OrganismHerpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) [Complete proteome] [HAMAP]
Taxonomic identifier316274 [NCBI]
Taxonomic lineageBacteria › Chloroflexi › Herpetosiphonales › Herpetosiphonaceae › Herpetosiphon

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4314313-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099708

Sequences

Sequence LengthMass (Da)Tools
A9AZ72 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: DD180921FF9A8119

FASTA43145,381
        10         20         30         40         50         60 
MKQTVSHAKR LRGAISVPGD KSISHRSVLF NALAEGNAEI TGFLPGADCL SSIACLRQMG 

        70         80         90        100        110        120 
VEIEHSDDKV RVFGRGLRGL REPSDVLDCG NSGTTLRLLA GLLAGQPFLS VLTGDASLRS 

       130        140        150        160        170        180 
RPQKRIVEPL RQLGAKLDGR DNGNRAPLVI RGTTIHGGNY ELPIASAQVK SALLLAGLTG 

       190        200        210        220        230        240 
DAPMRLSGKI VSRDHTERML IAMGIDLTVK DDEIVLYPPS HPVFPYPLSL HVPGDPSSAT 

       250        260        270        280        290        300 
FWWVAAAIHP DAEITTLGVG LNPSRTGALD VLKAMGADIT ISNERNEGAE PVGDVTVRGG 

       310        320        330        340        350        360 
GLRGTRIDGD LIPRLIDEIP VLAVAAACAV GETVVADAEE LRAKETDRVA TVVSELTAMG 

       370        380        390        400        410        420 
ATLEATPDGM IIAGGGELQG AHVQSHGDHR IAMALAVAGL VAEGETIIDE AEAVTVSYPT 

       430 
FWQHYAQIKE A

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References

[1]"Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Bryant D.A., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 23779 / DSM 785.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000875 Genomic DNA. Translation: ABX03618.1.
RefSeqYP_001543746.1. NC_009972.1.

3D structure databases

ProteinModelPortalA9AZ72.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9AZ72.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5732856.
GenomeReviewsGene locus Haur_0970 in contig CP000875_GR.
KEGGhau:Haur_0970.
PATRIC22118891. VBIHerAur93466_0989.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMALECANIS.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycHAUR316274:HAUR_0970-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_HERA2
AccessionPrimary (citable) accession number: A9AZ72
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 15, 2008
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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