A9AYK6 (FABZ_HERA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Short name=(3R)-hydroxymyristoyl ACP dehydrase
EC=4.2.1.-

Gene names

Name:	fabZ
Ordered Locus Names:	Haur_2344

Organism

Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) [Complete proteome] [HAMAP]

Taxonomic identifier

316274 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Herpetosiphonales › Herpetosiphonaceae › Herpetosiphon

Protein attributes

Sequence length	141 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in saturated fatty acids biosynthesis By similarity. HAMAP MF_00406
Subcellular location	Cytoplasm By similarity HAMAP MF_00406.
Sequence similarities	Belongs to the thioester dehydratase family. FabZ subfamily.

Ontologies

Keywords
Biological process	Lipid A biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 141	141	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase HAMAP MF_00406		PRO_1000123644
Sites
	Active site	48	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9AYK6 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 33041B93C20FCBEE	FASTA	141	15,461
	10 20 30 40 50 60 MLTVEDILAI LPHRPPFLLV DRILEIEDGL RAVGLKNVTM NEPFFVGHFP GRPVMPGVLI 70 80 90 100 110 120 VEALAQVGAV IILRQPEYVG KIVMFAGIDD FRFKRPVTPG DTLKLEVSLD KMRRRIGKGQ 130 140 AKATVDGTVV AEGGLMFAIV D

References

[1]

"Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Bryant D.A., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 23779 / DSM 785.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000875 Genomic DNA. Translation: ABX04984.1.
RefSeq	YP_001545112.1. NC_009972.1.
3D structure databases
ProteinModelPortal	A9AYK6.
ModBase	Search...
Protein-protein interaction databases
STRING	A9AYK6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5736878.
GenomeReviews	Gene locus Haur_2344 in contig CP000875_GR.
KEGG	hau:Haur_2344.
PATRIC	22121753. VBIHerAur93466_2405.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG433282.
OMA	NVSANES.
Enzyme and pathway databases
BioCyc	HAUR316274:HAUR_2344-MONOMER.
Family and domain databases
HAMAP	MF_00406. FabZ. [Tree]
InterPro	IPR013114. FabA_FabZ. IPR010084. FabZ. [Graphical view]
KO	K02372.
Pfam	PF07977. FabA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01750. FabZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FABZ_HERA2

Accession

Primary (citable) accession number: A9AYK6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	January 15, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program