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A9ARG7 (XYLA_BURM1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:Bmul_4207, BMULJ_04298
OrganismBurkholderia multivorans (strain ATCC 17616 / 249) [Complete proteome] [HAMAP]
Taxonomic identifier395019 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_00455

Subunit structure

Homotetramer By similarity. HAMAP MF_00455

Subcellular location

Cytoplasm By similarity HAMAP MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

xylose isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 440440Xylose isomerase HAMAP MF_00455
PRO_1000200284

Sites

Active site1001 By similarity
Active site1031 By similarity
Metal binding2311Magnesium 1 By similarity
Metal binding2671Magnesium 1 By similarity
Metal binding2671Magnesium 2 By similarity
Metal binding2701Magnesium 2 By similarity
Metal binding2951Magnesium 1 By similarity
Metal binding3061Magnesium 2 By similarity
Metal binding3081Magnesium 2 By similarity
Metal binding3381Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
A9ARG7 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: CFAEAFD786C0442A

FASTA44049,844
        10         20         30         40         50         60 
MSYFEHIPAI RYEGPQSDNP LAYHHYDRTK RVLGKTLEEH LRIAVCYWHT FVWPGHDIFG 

        70         80         90        100        110        120 
QGAFRRPWQQ PGDALERARQ KADAAFEFFT KLGTPFYTFH DTDVAPEGDS LREYVDNFAR 

       130        140        150        160        170        180 
MVDYLGERQQ ASGVRLLWGT ANLFSHPRFA AGAATNPNPD VFAWAATQVR HALDATHRLG 

       190        200        210        220        230        240 
GENYVLWGGR EGYETLLNTD LKREREQFAR FLSMVVEHKH RIGFRGALLI EPKPQEPTKH 

       250        260        270        280        290        300 
QYDYDVATVH GFLTQYGLQD EIRVNIEANH ATLAGHSFHH EIANAFALGV FGSVDANRGD 

       310        320        330        340        350        360 
PQNGWDTDQF PNSVEELTLA FYEILRHGGF TTGGMNFDAK VRRQSVDPED LFYGHVGAID 

       370        380        390        400        410        420 
VLALALERAA VLVENDRLEA MRRQRYAQWD DAFGRKILSG GYTLESLAAD ALARGVNPQH 

       430        440 
ASGAQERLEN IVNQAIYALR

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia multivorans ATCC 17616."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17616 / 249.
[2]"Complete genome sequence of Burkholderia multivorans ATCC 17616."
Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17616 / 249.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000869 Genomic DNA. Translation: ABX17888.1.
AP009386 Genomic DNA. Translation: BAG46155.1.
RefSeqYP_001584180.1. NC_010086.1.
YP_001948691.1. NC_010805.1.

3D structure databases

ProteinModelPortalA9ARG7.
SMRA9ARG7. Positions 2-438.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9ARG7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5768147.
6362527.
GenomeReviewsGene locus BMULJ_04298 in contig AP009386_GR.
Gene locus Bmul_4207 in contig CP000869_GR.
KEGGbmj:BMULJ_04298.
bmu:Bmul_4207.
PATRIC19170687. VBIBurMul203716_5380.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG297199.
OMALLGWDTD.
ProtClustDBPRK05474.

Family and domain databases

HAMAPMF_00455. Xylose_isom_A.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01805.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02630. Xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_BURM1
AccessionPrimary (citable) accession number: A9ARG7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: January 15, 2008
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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