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A9AQN4 (A9AQN4_BURM1) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:Bmul_3991, BMULJ_04511
OrganismBurkholderia multivorans (strain ATCC 17616 / 249) [Complete proteome] [HAMAP]
Taxonomic identifier395019 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
A9AQN4 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 0CE8FB5AB23C63B1

FASTA27628,552
        10         20         30         40         50         60 
MRNGHAHHGH GPVDVAMIGF GAIGAAVYRA VEHDASLRVA HVIVPEHQRD AVQRDLGGAV 

        70         80         90        100        110        120 
DVVSSVDALA CRPEFALECA GHSALVDHVV PLLKSGTDCA VASIGALSDL ALLDALSQAA 

       130        140        150        160        170        180 
DEGDATLTLL SGAIGGIDAL ASAKQGGLDE VLYVGRKPPL GWLGTPAEAL CDLRTMTEEK 

       190        200        210        220        230        240 
VIFEGTARDA ARLYPKNANV AATVALAGVG LDATRVRLIA DPAVARNVHR ITARGAFGEM 

       250        260        270 
SLEMSGKPLP DNPKTSALTA FSAIRALRNR AARCVI

« Hide

References

[1]"Complete genome sequence of Burkholderia multivorans ATCC 17616."
Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17616 EMBL BAG46362.1 and ATCC 17616 / 249 [Tohoku University].
[2]"Complete sequence of chromosome 2 of Burkholderia multivorans ATCC 17616."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17616 / 249 [DOE JGI].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000869 Genomic DNA. Translation: ABX17674.1.
AP009386 Genomic DNA. Translation: BAG46362.1.
RefSeqYP_001583966.1. NC_010086.1.
YP_001948898.1. NC_010805.1.

3D structure databases

ProteinModelPortalA9AQN4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9AQN4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5769900.
6361990.
GenomeReviewsGene locus BMULJ_04511 in contig AP009386_GR.
Gene locus Bmul_3991 in contig CP000869_GR.
KEGGbmj:BMULJ_04511.
bmu:Bmul_3991.
PATRIC19171169. VBIBurMul203716_5621.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG649642.
OMAECAGHSA.
ProtClustDBPRK13303.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA9AQN4_BURM1
AccessionPrimary (citable) accession number: A9AQN4
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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