A9ANW2 (A9ANW2_BURM1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Beta-lactamase EMBL ABX17373.1
EC=3.5.2.6 EMBL ABX17373.1

Gene names

Name:	ampC EMBL BAG46675.1
Ordered Locus Names:	Bmul_3689, BMULJ_04828

Organism

Burkholderia multivorans (strain ATCC 17616 / 249) [Complete proteome] [HAMAP]

Taxonomic identifier

395019 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

A beta-lactam + H2O = a substituted beta-amino acid. SAAS SAAS012338

Ontologies

Keywords
Biological process	Antibiotic resistance SAAS SAAS012338
Domain	Signal EMBL ABX17373.1
Molecular function	Hydrolase SAAS SAAS023650 EMBL ABX17373.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	beta-lactam antibiotic catabolic process Inferred from electronic annotation. Source: InterPro response to antibiotic Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	beta-lactamase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential EMBL ABX17373.1
	Chain	29 – 302	274	Potential EMBL ABX17373.1		PRO_5000285633

Sequences

	Sequence		Length	Mass (Da)
	A9ANW2 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: D7B6D354C097C5FA	FASTA	302	31,726
	10 20 30 40 50 60 MTHSSQRRIL LLAAATAPLA LSLGACAARD ATVSDAASPV GAAPASFAAL ERAAGGRLGV 70 80 90 100 110 120 CAIDTATGRR ALHRADERFP FCSTFKAMLG AAVLAQSVAH PGLLQQRVTY GRSDLVNYSP 130 140 150 160 170 180 VTERHVDTGM TVAELCAATI QYSDNTAANE LMKRIGGPAA VTAYARSIGD DTFRLDRWET 190 200 210 220 230 240 ELNTALPGDL RDTTTPAAMA ANLRVLVLGD ALPPAQRAQL IEWLRGNKVG DKRIRAGVPT 250 260 270 280 290 300 GWRVGDKTGT GDYGTTNDVG VLWPPSRAPI VLAVYYTQTR ADAKAKDDVI AAATRIASAT LA

References

[1]

"Complete genome sequence of Burkholderia multivorans ATCC 17616." Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17616 EMBL BAG46675.1 and ATCC 17616 / 249.

[2]

"Complete sequence of chromosome 2 of Burkholderia multivorans ATCC 17616." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17616 / 249.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000869 Genomic DNA. Translation: ABX17373.1. AP009386 Genomic DNA. Translation: BAG46675.1.
RefSeq	YP_001583665.1. NC_010086.1. YP_001949211.1. NC_010805.1.
3D structure databases
ProteinModelPortal	A9ANW2.
SMR	A9ANW2. Positions 47-298.
ModBase	Search...
Protein-protein interaction databases
STRING	A9ANW2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5769488. 6361554.
GenomeReviews	Gene locus BMULJ_04828 in contig AP009386_GR. Gene locus Bmul_3689 in contig CP000869_GR.
KEGG	bmj:BMULJ_04828. bmu:Bmul_3689.
PATRIC	19171773. VBIBurMul203716_5923.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG535713.
OMA	ATYDNQL.
ProtClustDB	CLSK941638.
Family and domain databases
InterPro	IPR001466. Beta-lactam-related. IPR012338. Beta-lactam/transpept-like. IPR000871. Beta-lactam_class-A/D. IPR023650. Beta-lactam_class-A_AS. IPR006311. TAT_signal. [Graphical view]
Gene3D	G3DSA:3.40.710.10. G3DSA:3.40.710.10. 1 hit.
KO	K01467.
Pfam	PF00144. Beta-lactamase. 1 hit. [Graphical view]
PRINTS	PR00118. BLACTAMASEA.
SUPFAM	SSF56601. PBP_transp_fold. 1 hit.
PROSITE	PS00146. BETA_LACTAMASE_A. 1 hit. PS51318. TAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9ANW2_BURM1

Accession

Primary (citable) accession number: A9ANW2

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)