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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

gabT

Organism
Burkholderia multivorans (strain ATCC 17616 / 249)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciBMUL395019:GIYO-5158-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported (EC:2.6.1.19Imported)
Gene namesi
Name:gabTImported
Ordered Locus Names:Bmul_3364Imported, BMULJ_05162Imported
OrganismiBurkholderia multivorans (strain ATCC 17616 / 249)Imported
Taxonomic identifieri395019 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000007064: Chromosome 2, UP000008815: Chromosome 2

Interactioni

Protein-protein interaction databases

STRINGi395019.Bmul_3364.

Structurei

3D structure databases

ProteinModelPortaliA9AM19.
SMRiA9AM19. Positions 4-424.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiGQRLTNT.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9AM19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVKNADLLA RKNAATPRGV GVMCDFYAAR AENAELWDVE GRRFIDFAAG
60 70 80 90 100
IAVLNTGHRH PKIVKAIAEQ LELFTHTAYQ IVPYASYVEL AEKINERAPG
110 120 130 140 150
DFPKKTAFFT TGAEAVENAI KIARAATGRP GVIAFSGGFH GRTMMGMALT
160 170 180 190 200
GKVAPYKLNF GPFPGDVFHA PYPNAVHGVT TADSIKAIEM LFKADIDPKR
210 220 230 240 250
VAAIIFEPVQ GEGGFNPAPA EFVRALRKIC NEHGILLIAD EVQTGFARTG
260 270 280 290 300
KLFAMQHYDV LADLITMAKS LAGGMPLSGV VGRADVMDAA APGGLGGTYA
310 320 330 340 350
GNPLAVASAH AVLEIIDEEK LCERATQLGD TLKAKLNALQ AEVPQIADVR
360 370 380 390 400
GPGAMIAVEF MKPGTGEPDA EFTKRVQARA LERGLLLLVC GVYSNVVRFL
410 420
FPLTIPQAVF DEALAILEEV LKETVGVPA
Length:429
Mass (Da):45,769
Last modified:January 15, 2008 - v1
Checksum:iC7EF9DC186FE6552
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000869 Genomic DNA. Translation: ABX17048.1.
AP009386 Genomic DNA. Translation: BAG47001.1.
RefSeqiYP_001583340.1. NC_010086.1.
YP_001949537.1. NC_010805.1.

Genome annotation databases

EnsemblBacteriaiABX17048; ABX17048; Bmul_3364.
BAG47001; BAG47001; BMULJ_05162.
GeneIDi5769957.
6361791.
KEGGibmj:BMULJ_05162.
bmu:Bmul_3364.
PATRICi19172483. VBIBurMul203716_6272.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000869 Genomic DNA. Translation: ABX17048.1.
AP009386 Genomic DNA. Translation: BAG47001.1.
RefSeqiYP_001583340.1. NC_010086.1.
YP_001949537.1. NC_010805.1.

3D structure databases

ProteinModelPortaliA9AM19.
SMRiA9AM19. Positions 4-424.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi395019.Bmul_3364.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABX17048; ABX17048; Bmul_3364.
BAG47001; BAG47001; BMULJ_05162.
GeneIDi5769957.
6361791.
KEGGibmj:BMULJ_05162.
bmu:Bmul_3364.
PATRICi19172483. VBIBurMul203716_6272.

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiGQRLTNT.
OrthoDBiEOG6QVRHN.

Enzyme and pathway databases

BioCyciBMUL395019:GIYO-5158-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of Burkholderia multivorans ATCC 17616."
    Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17616Imported and ATCC 17616 / 249Imported.
  2. "Complete sequence of chromosome 2 of Burkholderia multivorans ATCC 17616."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17616 / 249Imported.
  3. "Complete sequence of chromosome2 of Burkholderia multivorans ATCC 17616."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 17616Imported.

Entry informationi

Entry nameiA9AM19_BURM1
AccessioniPrimary (citable) accession number: A9AM19
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: January 7, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.