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A9AKZ0 (A9AKZ0_BURM1) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183
Gene names
Name:ald EMBL BAG45979.1
Ordered Locus Names:Bmul_4385, BMULJ_04122
OrganismBurkholderia multivorans (strain ATCC 17616 / 249) [Complete proteome] [HAMAP]
Taxonomic identifier395019 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183

Pathway

Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183

Sequence similarities

Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
   LigandNAD PIRNR PIRNR000183
   Molecular functionOxidoreductase PIRNR PIRNR000183 EMBL BAG45979.1
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionalanine dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A9AKZ0 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 0B8E264A9E3994AB

FASTA37138,494
        10         20         30         40         50         60 
MLIGVPKEIK NHEYRVGLTP AGARELTRHG HKVLVQRGAG TAIGLLDDDY AAAGAALCDG 

        70         80         90        100        110        120 
AEEVFARADM IVKVKEPQPA ECAMLRRGQL LYAYLHLAPD PEQAAPLVQS GAVCIAYETV 

       130        140        150        160        170        180 
TGPGGGLPLL APMSEVAGRM SIQVAATHLE SPRGGRGMLM AGVPGVPAAH VVVLGAGVVG 

       190        200        210        220        230        240 
TGALQMAVGL GARVTVLDTN VNRLRQLDLI FANRIATVCS NAQTIDEAIR DADVVIGAVL 

       250        260        270        280        290        300 
VPGASAPKLV TRDMIATMRA GAVVVDVAID QGGCFETSHP TTHADPTFVV DGVVHYCVAN 

       310        320        330        340        350        360 
MPGAVARTST FALNNATLGH ALALADKGWK QAMIDDPHLR AGLNVCDGHI TYEAVAQALR 

       370 
LPYVPAIDVL A

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References

[1]"Complete genome sequence of Burkholderia multivorans ATCC 17616."
Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17616 EMBL BAG45979.1 and ATCC 17616 / 249.
[2]"Complete sequence of chromosome 2 of Burkholderia multivorans ATCC 17616."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17616 / 249.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000869 Genomic DNA. Translation: ABX18065.1.
AP009386 Genomic DNA. Translation: BAG45979.1.
RefSeqYP_001584357.1. NC_010086.1.
YP_001948515.1. NC_010805.1.

3D structure databases

ProteinModelPortalA9AKZ0.
SMRA9AKZ0. Positions 1-371.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9AKZ0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5769815.
6362072.
GenomeReviewsGene locus BMULJ_04122 in contig AP009386_GR.
Gene locus Bmul_4385 in contig CP000869_GR.
KEGGbmj:BMULJ_04122.
bmu:Bmul_4385.
PATRIC19170309. VBIBurMul203716_5191.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG289735.
OMAAIGYETV.
ProtClustDBCLSK931331.

Family and domain databases

InterProIPR008143. Ala_DH/PNT_CS2.
IPR008141. Ala_DH/Pyr_transHydgase.
IPR007886. AlaDH/PNT_N.
IPR007698. AlaDH/PNT_NAD(H)-bd.
[Graphical view]
KOK00259.
PANTHERPTHR10160:SF3. PTHR10160:SF3. 1 hit.
PfamPF01262. AlaDh_PNT_C. 1 hit.
PF05222. AlaDh_PNT_N. 1 hit.
[Graphical view]
PIRSFPIRSF000183. Alanine_dh. 1 hit.
SMARTSM01002. AlaDh_PNT_C. 1 hit.
SM01003. AlaDh_PNT_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00518. AlaDH. 1 hit.
PROSITEPS00837. ALADH_PNT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA9AKZ0_BURM1
AccessionPrimary (citable) accession number: A9AKZ0
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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