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A9AKW7

- A9AKW7_BURM1

UniProt

A9AKW7 - A9AKW7_BURM1

Protein

Beta-galactosidase

Gene

lacZ

Organism
Burkholderia multivorans (strain ATCC 17616 / 249)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (15 Jan 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei103 – 1031SubstrateUniRule annotation
    Binding sitei141 – 1411SubstrateUniRule annotation
    Active sitei142 – 1421Proton donorUniRule annotation
    Active sitei313 – 3131NucleophileUniRule annotation
    Binding sitei321 – 3211SubstrateUniRule annotation

    GO - Molecular functioni

    1. beta-galactosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseUniRule annotationImported, Hydrolase

    Enzyme and pathway databases

    BioCyciBMUL395019:GIYO-5324-MONOMER.

    Protein family/group databases

    CAZyiGH42. Glycoside Hydrolase Family 42.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
    Short name:
    Beta-galUniRule annotation
    Gene namesi
    Name:lacZImported
    Ordered Locus Names:Bmul_3197Imported, BMULJ_05328Imported
    OrganismiBurkholderia multivorans (strain ATCC 17616 / 249)Imported
    Taxonomic identifieri395019 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
    ProteomesiUP000007064: Chromosome 2, UP000008815: Chromosome 2

    Subcellular locationi

    GO - Cellular componenti

    1. beta-galactosidase complex Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi395019.Bmul_3197.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 42 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1874.
    HOGENOMiHOG000117811.
    KOiK12308.
    OMAiMLGVCYY.
    OrthoDBiEOG6HMX9F.

    Family and domain databases

    Gene3Di2.60.40.1180. 1 hit.
    3.20.20.80. 1 hit.
    3.40.50.880. 1 hit.
    InterProiIPR013738. Beta_galactosidase_Trimer.
    IPR029062. Class_I_gatase-like.
    IPR013780. Glyco_hydro_13_b.
    IPR003476. Glyco_hydro_42.
    IPR013529. Glyco_hydro_42_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF02449. Glyco_hydro_42. 1 hit.
    PF08532. Glyco_hydro_42M. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001084. B-galactosidase. 1 hit.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    SSF52317. SSF52317. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A9AKW7-1 [UniParc]FASTAAdd to Basket

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    MRVGVCYYPE HWPESMWADD ARRMKALGIA QVRIAEFAWS RIEPSPGEYD    50
    WGWLDRAVDV LAAAGLDIVM CTPTATPPKW LIDRHPEILA IGADGRPRTF 100
    GSRRHYDFSS PVYYDASRQI CTAVAERYGR HPAVRFWQTD NEMGCHQTVV 150
    SYSPAALARF REWLKARYGT IDALNRAWGT VFWSMEYRDF DEIDAPVGTV 200
    TEAHPTHRLD YRRFASDEVV RYHRMQVDVI RAHSPGRPVA HNFMQLFTDF 250
    DHYAVARDLD VATWDSYPLG ALEEHWFAPD VKARWLRTGH PDFASFNHDL 300
    YRGMSKLPFW VMEQQPGPVN WAHWNPAPLP GMVRLWSWEA FAHGAGCVSY 350
    FRWRQAPFAQ EQMHAGLHTP DDRLDEGGRE AERVAHEIAV VHGADAHADA 400
    AVHARVALVF DYEAKWLLDV QPQGADFQYA RIAFEYYSAL RALGLDVDVI 450
    SAQAPLDGYR LVVVPPLPIV PDDFAARLAA SGAHAVFGPR TGSKTVDLQI 500
    PPTLPPGALA SILPLRVWRV ESLRPNVTER VDGALVDGTP FAGHARHWRD 550
    LVELRDAQRT VVRARFADDH PAWLSHGTLH YWAALFDDAT TAQLFASVAA 600
    EAGLAPTPLA DGVRISRRGG LTYVFNYGDT VHTIDAVPPA AFVVGSADVE 650
    PRGVAVYRSP V 661
    Length:661
    Mass (Da):74,176
    Last modified:January 15, 2008 - v1
    Checksum:iD9D654062A2E4658
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000869 Genomic DNA. Translation: ABX16881.1.
    AP009386 Genomic DNA. Translation: BAG47166.1.
    RefSeqiYP_001583173.1. NC_010086.1.
    YP_001949702.1. NC_010805.1.

    Genome annotation databases

    EnsemblBacteriaiABX16881; ABX16881; Bmul_3197.
    BAG47166; BAG47166; BMULJ_05328.
    GeneIDi5768083.
    6361892.
    KEGGibmj:BMULJ_05328.
    bmu:Bmul_3197.
    PATRICi19172845. VBIBurMul203716_6453.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000869 Genomic DNA. Translation: ABX16881.1 .
    AP009386 Genomic DNA. Translation: BAG47166.1 .
    RefSeqi YP_001583173.1. NC_010086.1.
    YP_001949702.1. NC_010805.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 395019.Bmul_3197.

    Protein family/group databases

    CAZyi GH42. Glycoside Hydrolase Family 42.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABX16881 ; ABX16881 ; Bmul_3197 .
    BAG47166 ; BAG47166 ; BMULJ_05328 .
    GeneIDi 5768083.
    6361892.
    KEGGi bmj:BMULJ_05328.
    bmu:Bmul_3197.
    PATRICi 19172845. VBIBurMul203716_6453.

    Phylogenomic databases

    eggNOGi COG1874.
    HOGENOMi HOG000117811.
    KOi K12308.
    OMAi MLGVCYY.
    OrthoDBi EOG6HMX9F.

    Enzyme and pathway databases

    BioCyci BMUL395019:GIYO-5324-MONOMER.

    Family and domain databases

    Gene3Di 2.60.40.1180. 1 hit.
    3.20.20.80. 1 hit.
    3.40.50.880. 1 hit.
    InterProi IPR013738. Beta_galactosidase_Trimer.
    IPR029062. Class_I_gatase-like.
    IPR013780. Glyco_hydro_13_b.
    IPR003476. Glyco_hydro_42.
    IPR013529. Glyco_hydro_42_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF02449. Glyco_hydro_42. 1 hit.
    PF08532. Glyco_hydro_42M. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001084. B-galactosidase. 1 hit.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    SSF52317. SSF52317. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Burkholderia multivorans ATCC 17616."
      Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M.
      Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 17616Imported and ATCC 17616 / 249Imported.
    2. "Complete sequence of chromosome 2 of Burkholderia multivorans ATCC 17616."
      Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 17616 / 249Imported.
    3. "Complete sequence of chromosome2 of Burkholderia multivorans ATCC 17616."
      US DOE Joint Genome Institute
      Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: ATCC 17616Imported.

    Entry informationi

    Entry nameiA9AKW7_BURM1
    AccessioniPrimary (citable) accession number: A9AKW7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 15, 2008
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3