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A9AKW7

- A9AKW7_BURM1

UniProt

A9AKW7 - A9AKW7_BURM1

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Protein

Beta-galactosidase

Gene

lacZ

Organism
Burkholderia multivorans (strain ATCC 17616 / 249)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei103 – 1031SubstrateUniRule annotation
Binding sitei141 – 1411SubstrateUniRule annotation
Active sitei142 – 1421Proton donorUniRule annotation
Active sitei313 – 3131NucleophileUniRule annotation
Binding sitei321 – 3211SubstrateUniRule annotation

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Enzyme and pathway databases

BioCyciBMUL395019:GIYO-5324-MONOMER.

Protein family/group databases

CAZyiGH42. Glycoside Hydrolase Family 42.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
Short name:
Beta-galUniRule annotation
Gene namesi
Name:lacZImported
Ordered Locus Names:Bmul_3197Imported, BMULJ_05328Imported
OrganismiBurkholderia multivorans (strain ATCC 17616 / 249)Imported
Taxonomic identifieri395019 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000007064: Chromosome 2, UP000008815: Chromosome 2

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi395019.Bmul_3197.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 42 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1874.
HOGENOMiHOG000117811.
KOiK12308.
OMAiMLGVCYY.
OrthoDBiEOG6HMX9F.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR013780. Glyco_hydro_13_b.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.

Sequencei

Sequence statusi: Complete.

A9AKW7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRVGVCYYPE HWPESMWADD ARRMKALGIA QVRIAEFAWS RIEPSPGEYD
60 70 80 90 100
WGWLDRAVDV LAAAGLDIVM CTPTATPPKW LIDRHPEILA IGADGRPRTF
110 120 130 140 150
GSRRHYDFSS PVYYDASRQI CTAVAERYGR HPAVRFWQTD NEMGCHQTVV
160 170 180 190 200
SYSPAALARF REWLKARYGT IDALNRAWGT VFWSMEYRDF DEIDAPVGTV
210 220 230 240 250
TEAHPTHRLD YRRFASDEVV RYHRMQVDVI RAHSPGRPVA HNFMQLFTDF
260 270 280 290 300
DHYAVARDLD VATWDSYPLG ALEEHWFAPD VKARWLRTGH PDFASFNHDL
310 320 330 340 350
YRGMSKLPFW VMEQQPGPVN WAHWNPAPLP GMVRLWSWEA FAHGAGCVSY
360 370 380 390 400
FRWRQAPFAQ EQMHAGLHTP DDRLDEGGRE AERVAHEIAV VHGADAHADA
410 420 430 440 450
AVHARVALVF DYEAKWLLDV QPQGADFQYA RIAFEYYSAL RALGLDVDVI
460 470 480 490 500
SAQAPLDGYR LVVVPPLPIV PDDFAARLAA SGAHAVFGPR TGSKTVDLQI
510 520 530 540 550
PPTLPPGALA SILPLRVWRV ESLRPNVTER VDGALVDGTP FAGHARHWRD
560 570 580 590 600
LVELRDAQRT VVRARFADDH PAWLSHGTLH YWAALFDDAT TAQLFASVAA
610 620 630 640 650
EAGLAPTPLA DGVRISRRGG LTYVFNYGDT VHTIDAVPPA AFVVGSADVE
660
PRGVAVYRSP V
Length:661
Mass (Da):74,176
Last modified:January 15, 2008 - v1
Checksum:iD9D654062A2E4658
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000869 Genomic DNA. Translation: ABX16881.1.
AP009386 Genomic DNA. Translation: BAG47166.1.
RefSeqiWP_012216211.1. NC_010805.1.
YP_001583173.1. NC_010086.1.
YP_001949702.1. NC_010805.1.

Genome annotation databases

EnsemblBacteriaiABX16881; ABX16881; Bmul_3197.
BAG47166; BAG47166; BMULJ_05328.
GeneIDi5768083.
6361892.
KEGGibmj:BMULJ_05328.
bmu:Bmul_3197.
PATRICi19172845. VBIBurMul203716_6453.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000869 Genomic DNA. Translation: ABX16881.1 .
AP009386 Genomic DNA. Translation: BAG47166.1 .
RefSeqi WP_012216211.1. NC_010805.1.
YP_001583173.1. NC_010086.1.
YP_001949702.1. NC_010805.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 395019.Bmul_3197.

Protein family/group databases

CAZyi GH42. Glycoside Hydrolase Family 42.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX16881 ; ABX16881 ; Bmul_3197 .
BAG47166 ; BAG47166 ; BMULJ_05328 .
GeneIDi 5768083.
6361892.
KEGGi bmj:BMULJ_05328.
bmu:Bmul_3197.
PATRICi 19172845. VBIBurMul203716_6453.

Phylogenomic databases

eggNOGi COG1874.
HOGENOMi HOG000117811.
KOi K12308.
OMAi MLGVCYY.
OrthoDBi EOG6HMX9F.

Enzyme and pathway databases

BioCyci BMUL395019:GIYO-5324-MONOMER.

Family and domain databases

Gene3Di 2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProi IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR013780. Glyco_hydro_13_b.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF02449. Glyco_hydro_42. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view ]
PIRSFi PIRSF001084. B-galactosidase. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of Burkholderia multivorans ATCC 17616."
    Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17616Imported and ATCC 17616 / 249Imported.
  2. "Complete sequence of chromosome 2 of Burkholderia multivorans ATCC 17616."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17616 / 249Imported.
  3. "Complete sequence of chromosome2 of Burkholderia multivorans ATCC 17616."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 17616Imported.

Entry informationi

Entry nameiA9AKW7_BURM1
AccessioniPrimary (citable) accession number: A9AKW7
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: November 26, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3