A9AKV9 (A9AKV9_BURM1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malate synthase G RuleBase RU003572 HAMAP MF_00641
EC=2.3.3.9 RuleBase RU003572 HAMAP MF_00641

Gene names

Name:	glcB HAMAP MF_00641 EMBL BAG47174.1
Ordered Locus Names:	Bmul_3189, BMULJ_05336

Organism

Burkholderia multivorans (strain ATCC 17616 / 249) [Complete proteome] [HAMAP]

Taxonomic identifier

395019 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	724 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. SAAS SAAS006253 RuleBase RU003572 HAMAP MF_00641
Pathway	Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. SAAS SAAS006253 RuleBase RU003572 HAMAP MF_00641
Subunit structure	Monomer By similarity. SAAS SAAS006253 HAMAP MF_00641
Subcellular location	Cytoplasm By similarity RuleBase RU003572 HAMAP MF_00641.
Sequence similarities	Belongs to the malate synthase family. GlcB subfamily. RuleBase RU003572 HAMAP MF_00641

Ontologies

Keywords
Biological process	Glyoxylate bypass SAAS SAAS006253 RuleBase RU003572 HAMAP MF_00641 Tricarboxylic acid cycle SAAS SAAS006253 RuleBase RU003572 HAMAP MF_00641
Cellular component	Cytoplasm SAAS SAAS006253 HAMAP MF_00641
Molecular function	Acyltransferase EMBL ABX16873.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate cycle Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	malate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9AKV9 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 7470302BC89B87A7	FASTA	724	78,836
	10 20 30 40 50 60 MIDHDGLQVA PALSQFIENE ALPGTGIDQA AFWRGFSALV HDLAPRNREL LAERDRLQSE 70 80 90 100 110 120 LDAWHRAHPG PVRDLAAYRA FLEQIGYLVP TPADVAATTA NVDSEIATQA GPQLVVPLSN 130 140 150 160 170 180 ARYALNAANA RWGSLYDALY GTDALPEDNG AERTATYNPT RGQRVIDYAR NVLDNAAPLA 190 200 210 220 230 240 GASHRDALRY RVQDGQLAVE TGKGIVHLAQ PAQFVGYQGA ADAPSAILLK HNGLHLEIQI 250 260 270 280 290 300 DGSTPIGRAD VANVKDVVLE AAVSTIIDCE DSVAAVDAED KVQLYRNWLG LMQGTLVEEV 310 320 330 340 350 360 SKGGKTFTRR LNADREYTTP DGGTLTLHGR SLLFVRNVGH LMTIGAVLDR DGNEIPEGIL 370 380 390 400 410 420 DGVVTTLCAL HDLKSKRNSR TGSIYIVKPK MHGPAEVAFA DTLFARIEDL YGLPRNTLKM 430 440 450 460 470 480 GIMDEERRTS VNLAACIAAA AARVAFINTG FLDRTGDEMH SAMEAGPMIR KGDMKSSAWI 490 500 510 520 530 540 AAYERNNVLA GLSAGLRGRA QIGKGMWAMP DLMHAMLEQK IAHPRAGANT AWVPSPTAAT 550 560 570 580 590 600 LHALHYHLVD VQAVQQELER TPYASERDAL LDGLLTVPVV ERAAWSDEEI LREVENNAQG 610 620 630 640 650 660 ILGYVVRWVE QGVGCSKVPD IHDVGLMEDR ATLRISSQHI ANWLRHGVIT EAFVLDVFKR 670 680 690 700 710 720 MARVVDQQNA GDPNYRPMAP DYDRSVAFQA ACALALHGTS QPSGYTEPLL HRFRLAFKAQ QAQA

References

[1]

"Complete genome sequence of Burkholderia multivorans ATCC 17616." Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17616 EMBL BAG47174.1 and ATCC 17616 / 249.

[2]

"Complete sequence of chromosome 2 of Burkholderia multivorans ATCC 17616." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17616 / 249.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000869 Genomic DNA. Translation: ABX16873.1. AP009386 Genomic DNA. Translation: BAG47174.1.
RefSeq	YP_001583165.1. NC_010086.1. YP_001949710.1. NC_010805.1.
3D structure databases
ProteinModelPortal	A9AKV9.
SMR	A9AKV9. Positions 7-715.
ModBase	Search...
Protein-protein interaction databases
STRING	A9AKV9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5768804. 6361895.
GenomeReviews	Gene locus BMULJ_05336 in contig AP009386_GR. Gene locus Bmul_3189 in contig CP000869_GR.
KEGG	bmj:BMULJ_05336. bmu:Bmul_3189.
PATRIC	19172861. VBIBurMul203716_6461.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG350005.
OMA	ENANWSV.
ProtClustDB	PRK02999.
Family and domain databases
HAMAP	MF_00641. Malate_synth_G. [Tree]
InterPro	IPR011076. Malate_synth-like. IPR023310. Malate_synth_G_beta_sub_dom. IPR001465. Malate_synthase. IPR006253. Malate_synthG. [Graphical view]
Gene3D	G3DSA:2.170.170.11. Malate_synth_G_beta_sub_dom. 2 hits.
KO	K01638.
PANTHER	PTHR21631:SF1. Malate_synthase. 1 hit.
Pfam	PF01274. Malate_synthase. 1 hit. [Graphical view]
SUPFAM	SSF51645. Malat_synth_like. 1 hit.
TIGRFAMs	TIGR01345. Malate_syn_G. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9AKV9_BURM1

Accession

Primary (citable) accession number: A9AKV9

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)