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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Burkholderia multivorans (strain ATCC 17616 / 249)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei381 – 3811UniRule annotation
Active sitei503 – 5031UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBMUL395019:GIYO-1884-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Bmul_1357, BMULJ_01886
OrganismiBurkholderia multivorans (strain ATCC 17616 / 249)
Taxonomic identifieri395019 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000007064: Chromosome 1, UP000008815: Chromosome 1

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 540540Glucose-6-phosphate isomerasePRO_1000125702Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi395019.Bmul_1357.

Structurei

3D structure databases

ProteinModelPortaliA9AJR8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9AJR8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTLNSLPAWT ALQSHFEQIR HARLRDWFAP QNDPAPTRAE RFTFSGGGLA
60 70 80 90 100
ADFSKNRITD ETLRLLVQLA REARVEARRD AMFAGEIVNP TEGRAALHTA
110 120 130 140 150
LRATDPHAPF HAQVSAERAK MATFARAVRN GTWTGHTGKR IRHVINIGIG
160 170 180 190 200
GSDLGPKMVT HALRHVATRD ISMHFVSNVD GADLARVLEQ VDPEETLAIV
210 220 230 240 250
VSKTFTTLET MTNARSLRDW FVAKGCPEDA LAKHFVGVSA NPAEVVKFGI
260 270 280 290 300
AADNVFEMWD WVGGRYSLWS AVGLSIMIAI GPEQFDELLA GANDMDRHFR
310 320 330 340 350
EAPLERNLPV LLGLIGIWYR NFFGSQSYLV APYSEALHYL PSYLQQLEME
360 370 380 390 400
SNGKSARLDG RFVDYPTAAV TWGEPGTNGQ HAFFQMLHQG PTIVPIDFIA
410 420 430 440 450
VLTPEHPLAS HHPKLLANCF AQSEALMLGR TLEEARKVAG PGKEDLAPHL
460 470 480 490 500
TFPGNRPTTT LLVDALTPRS LGALIALYEH KVLVQATVWD INPFDQWGVE
510 520 530 540
LGKILGKVVE ADLAADALDT AKHDSSTTAL IARARAALKR
Length:540
Mass (Da):59,399
Last modified:January 15, 2008 - v1
Checksum:i1A27BE526A2F770B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000868 Genomic DNA. Translation: ABX15045.1.
AP009385 Genomic DNA. Translation: BAG43806.1.
RefSeqiYP_001579542.1. NC_010084.1.
YP_001946342.1. NC_010804.1.

Genome annotation databases

EnsemblBacteriaiABX15045; ABX15045; Bmul_1357.
BAG43806; BAG43806; BMULJ_01886.
GeneIDi5764892.
6358252.
KEGGibmj:BMULJ_01886.
bmu:Bmul_1357.
PATRICi19165589. VBIBurMul203716_2870.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000868 Genomic DNA. Translation: ABX15045.1.
AP009385 Genomic DNA. Translation: BAG43806.1.
RefSeqiYP_001579542.1. NC_010084.1.
YP_001946342.1. NC_010804.1.

3D structure databases

ProteinModelPortaliA9AJR8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi395019.Bmul_1357.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABX15045; ABX15045; Bmul_1357.
BAG43806; BAG43806; BMULJ_01886.
GeneIDi5764892.
6358252.
KEGGibmj:BMULJ_01886.
bmu:Bmul_1357.
PATRICi19165589. VBIBurMul203716_2870.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciBMUL395019:GIYO-1884-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia multivorans ATCC 17616."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17616 / 249.
  2. "Complete genome sequence of Burkholderia multivorans ATCC 17616."
    Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17616 / 249.

Entry informationi

Entry nameiG6PI_BURM1
AccessioniPrimary (citable) accession number: A9AJR8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: January 15, 2008
Last modified: February 4, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.