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A9AJR8

- G6PI_BURM1

UniProt

A9AJR8 - G6PI_BURM1

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, Bmul_1357, BMULJ_01886
Organism
Burkholderia multivorans (strain ATCC 17616 / 249)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei381 – 3811 By similarity
Active sitei503 – 5031 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBMUL395019:GIYO-1884-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:Bmul_1357, BMULJ_01886
OrganismiBurkholderia multivorans (strain ATCC 17616 / 249)
Taxonomic identifieri395019 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000007064: Chromosome 1, UP000008815: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 540540Glucose-6-phosphate isomeraseUniRule annotation
PRO_1000125702Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi395019.Bmul_1357.

Structurei

3D structure databases

ProteinModelPortaliA9AJR8.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9AJR8-1 [UniParc]FASTAAdd to Basket

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MTLNSLPAWT ALQSHFEQIR HARLRDWFAP QNDPAPTRAE RFTFSGGGLA    50
ADFSKNRITD ETLRLLVQLA REARVEARRD AMFAGEIVNP TEGRAALHTA 100
LRATDPHAPF HAQVSAERAK MATFARAVRN GTWTGHTGKR IRHVINIGIG 150
GSDLGPKMVT HALRHVATRD ISMHFVSNVD GADLARVLEQ VDPEETLAIV 200
VSKTFTTLET MTNARSLRDW FVAKGCPEDA LAKHFVGVSA NPAEVVKFGI 250
AADNVFEMWD WVGGRYSLWS AVGLSIMIAI GPEQFDELLA GANDMDRHFR 300
EAPLERNLPV LLGLIGIWYR NFFGSQSYLV APYSEALHYL PSYLQQLEME 350
SNGKSARLDG RFVDYPTAAV TWGEPGTNGQ HAFFQMLHQG PTIVPIDFIA 400
VLTPEHPLAS HHPKLLANCF AQSEALMLGR TLEEARKVAG PGKEDLAPHL 450
TFPGNRPTTT LLVDALTPRS LGALIALYEH KVLVQATVWD INPFDQWGVE 500
LGKILGKVVE ADLAADALDT AKHDSSTTAL IARARAALKR 540
Length:540
Mass (Da):59,399
Last modified:January 15, 2008 - v1
Checksum:i1A27BE526A2F770B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000868 Genomic DNA. Translation: ABX15045.1.
AP009385 Genomic DNA. Translation: BAG43806.1.
RefSeqiYP_001579542.1. NC_010084.1.
YP_001946342.1. NC_010804.1.

Genome annotation databases

EnsemblBacteriaiABX15045; ABX15045; Bmul_1357.
BAG43806; BAG43806; BMULJ_01886.
GeneIDi5764892.
6358252.
KEGGibmj:BMULJ_01886.
bmu:Bmul_1357.
PATRICi19165589. VBIBurMul203716_2870.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000868 Genomic DNA. Translation: ABX15045.1 .
AP009385 Genomic DNA. Translation: BAG43806.1 .
RefSeqi YP_001579542.1. NC_010084.1.
YP_001946342.1. NC_010804.1.

3D structure databases

ProteinModelPortali A9AJR8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 395019.Bmul_1357.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX15045 ; ABX15045 ; Bmul_1357 .
BAG43806 ; BAG43806 ; BMULJ_01886 .
GeneIDi 5764892.
6358252.
KEGGi bmj:BMULJ_01886.
bmu:Bmul_1357.
PATRICi 19165589. VBIBurMul203716_2870.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci BMUL395019:GIYO-1884-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Burkholderia multivorans ATCC 17616."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17616 / 249.
  2. "Complete genome sequence of Burkholderia multivorans ATCC 17616."
    Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17616 / 249.

Entry informationi

Entry nameiG6PI_BURM1
AccessioniPrimary (citable) accession number: A9AJR8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: January 15, 2008
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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