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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Burkholderia multivorans (strain ATCC 17616 / 249)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:Bmul_1676, BMULJ_01567
OrganismiBurkholderia multivorans (strain ATCC 17616 / 249)
Taxonomic identifieri395019 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000008815 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001319091 – 254Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST254

Proteomic databases

PRIDEiA9AJ16

Interactioni

Protein-protein interaction databases

STRINGi395019.BMULJ_01567

Structurei

3D structure databases

ProteinModelPortaliA9AJ16
SMRiA9AJ16
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

A9AJ16-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVPWLGPDDP FPPVERALGP ATGAPGLLAA SADLLPSRLI DAYLRGIFPW
60 70 80 90 100
YSDGQPVLWW SPDPRMILVP DEFKVSPSLK KTLKRVLRDP AWEVRVDHDF
110 120 130 140 150
RGVMRACAQA PRRGQRGTWI TAEIIDAYSS LYRSGNAHSI ETWHDGRRVG
160 170 180 190 200
GLYGVAFGQM FFGESMYADV TDASKIALAA LVAHLREHGL EMIDCQQNTS
210 220 230 240 250
HLASLGGREI ARKAFVAHVR RAVAEPPIPW QFDKRVLAAL TGRTEPAAPS

GIER
Length:254
Mass (Da):28,073
Last modified:January 15, 2008 - v1
Checksum:i0D3160C18E69D1A2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000868 Genomic DNA Translation: ABX15364.1
AP009385 Genomic DNA Translation: BAG43493.1
RefSeqiWP_006414405.1, NC_010804.1

Genome annotation databases

EnsemblBacteriaiABX15364; ABX15364; Bmul_1676
BAG43493; BAG43493; BMULJ_01567
KEGGibmj:BMULJ_01567
bmu:Bmul_1676

Similar proteinsi

Entry informationi

Entry nameiLFTR_BURM1
AccessioniPrimary (citable) accession number: A9AJ16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: January 15, 2008
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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