A9AI32 (A9AI32_BURM1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase 1 HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE EMBL BAG42432.1
Synonyms:	aroE1 HAMAP MF_00222
Ordered Locus Names:	Bmul_2772, BMULJ_00465

Organism

Burkholderia multivorans (strain ATCC 17616 / 249) [Complete proteome] [HAMAP]

Taxonomic identifier

395019 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	288 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. SAAS SAAS011342 HAMAP MF_00222
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. SAAS SAAS011342 HAMAP MF_00222
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis SAAS SAAS011342 HAMAP MF_00222
Ligand	NADP SAAS SAAS011342 HAMAP MF_00222
Molecular function	Oxidoreductase SAAS SAAS011342 RuleBase RU004037 HAMAP MF_00222 EMBL BAG42432.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9AI32 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 39ED666E6EFF62E4	FASTA	288	29,504
	10 20 30 40 50 60 MSATAPTRGA DRYVVFGNPV AHSKSPFIHA QFAAQTGEAI DYTHRLAPVD GFEAAVRAFI 70 80 90 100 110 120 AEGGRGANVT VPFKLDAHAL ADTLSPRAAA AGAVNTLRFD ADGRIYGDNT DGVGLVRDIE 130 140 150 160 170 180 SNLGVSLAGA RILLLGAGGA ARGVVLPMLD RAPLSITIVN RTASKAEALV SQFMQAAHDA 190 200 210 220 230 240 GCTLAGGGPG EVRAQPYDVI VNATAGSLDA ALPECDAAAF GAGTLAYDMM YGAQPTVFMQ 250 260 270 280 HASSLGARTA DGLGMLVEQA AESFFVWRGV RPDGAPVLAA LRRALAAN

References

[1]

"Complete genome sequence of Burkholderia multivorans ATCC 17616." Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17616 EMBL BAG42432.1 and ATCC 17616 / 249.

[2]

"Complete sequence of chromosome 1 of Burkholderia multivorans ATCC 17616." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17616 / 249.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000868 Genomic DNA. Translation: ABX16456.1. AP009385 Genomic DNA. Translation: BAG42432.1.
RefSeq	YP_001580953.1. NC_010084.1. YP_001944968.1. NC_010804.1.
3D structure databases
ProteinModelPortal	A9AI32.
ModBase	Search...
Protein-protein interaction databases
STRING	A9AI32.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5767553. 6360065.
GenomeReviews	Gene locus BMULJ_00465 in contig AP009385_GR. Gene locus Bmul_2772 in contig CP000868_GR.
KEGG	bmj:BMULJ_00465. bmu:Bmul_2772.
PATRIC	19162618. VBIBurMul203716_1409.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553408.
OMA	VVFGNPI.
ProtClustDB	PRK00258.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9AI32_BURM1

Accession

Primary (citable) accession number: A9AI32

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)