Reviewed, UniProtKB/Swiss-Prot A9AHK2 (DCD_BURM1)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Bmul_0861, BMULJ_02397

Organism

Burkholderia multivorans (strain ATCC 17616 / 249) [Complete proteome] [HAMAP]

Taxonomic identifier

395019 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000096411

Sequences

	Sequence		Length	Mass (Da)
	A9AHK2-1 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 51562F4F9DC88E36	FASTA	189	21,356
	10 20 30 40 50 60 MSIKSDKWIR RMAEEHKMIE PFVPDQVRAS EDGRRIVSYG TSSYGYDIRC ADEFKIFTNI 70 80 90 100 110 120 NSTIVDPKNF DEGSFVDFKG DVCIIPPNSF ALARTVEYFR IPRTVLTVCL GKSTYARCGI 130 140 150 160 170 180 IVNVTPFEPE WEGYVTLEFS NTTPLPAKIY ANEGVAQVLF FESDEVCDVS YADRGGKYQG QRGVTLPKT

References

[1]

"Complete sequence of chromosome 1 of Burkholderia multivorans ATCC 17616." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Complete genome sequence of Burkholderia multivorans ATCC 17616." Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000868 Genomic DNA. Translation: ABX14555.1. AP009385 Genomic DNA. Translation: BAG44291.1.
RefSeq	YP_001579052.1. YP_001946827.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5766694. 6359609.
GenomeReviews	Gene locus BMULJ_02397 in contig AP009385_GR. Gene locus Bmul_0861 in contig CP000868_GR.
KEGG	bmj:BMULJ_02397. bmu:Bmul_0861.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CAQVLFF.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_BURM1

Accession

Primary (citable) accession number: A9AHK2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	January 15, 2008
Last modified:	November 3, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)