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A9AEY5 (A9AEY5_BURM1) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase 2 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase 2 HAMAP MF_01023
Gene names
Name:hisC EMBL BAG44638.1
Synonyms:hisC2 HAMAP MF_01023
Ordered Locus Names:Bmul_0510, BMULJ_02750
OrganismBurkholderia multivorans (strain ATCC 17616 / 249) [Complete proteome] [HAMAP]
Taxonomic identifier395019 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. SAAS SAAS005861 HAMAP MF_01023

Cofactor

Pyridoxal phosphate By similarity. SAAS SAAS005861 HAMAP MF_01023

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. SAAS SAAS005861 HAMAP MF_01023

Subunit structure

Homodimer By similarity. HAMAP MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Sequences

Sequence LengthMass (Da)Tools
A9AEY5 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 362022BF08CBC61C

FASTA35539,041
        10         20         30         40         50         60 
MSRYWSDVVQ QLVPYVPGEQ PALAHPVKLN TNENPYPPSP RVVAAIAREL GANGDTLRRY 

        70         80         90        100        110        120 
PDPLARALRE TVAAHHRLRP EQVFVGNGSD EVLAHTFQAL LKHDRPLRFP DITYSFYPTY 

       130        140        150        160        170        180 
ARLYGVDTRT VPLADDFSIR VDDYLDDGGG VLFPNPNAPT GRALPLADIE RIAAANPSSV 

       190        200        210        220        230        240 
VVIDEAYVDF GAQSAIALID RYPNLLVVHT TSKARSLAGM RVGFAFGDAA LIEALNRVKD 

       250        260        270        280        290        300 
SFNSYPLDRL AQVAAQAAYE DDAYFVSTCA RVVDSRTRLT QALDALGFDV VPSAANFVFA 

       310        320        330        340        350 
RHPAHDAGTL AAKLKEREIF VRHFRLPRID QHLRITVGTD AECEALVAAL RELLG

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References

[1]"Complete genome sequence of Burkholderia multivorans ATCC 17616."
Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E., Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N., Hattori M., Tsuda M.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17616 EMBL BAG44638.1 and ATCC 17616 / 249.
[2]"Complete sequence of chromosome 1 of Burkholderia multivorans ATCC 17616."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17616 / 249.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000868 Genomic DNA. Translation: ABX14205.1.
AP009385 Genomic DNA. Translation: BAG44638.1.
RefSeqYP_001578702.1. NC_010084.1.
YP_001947174.1. NC_010804.1.

3D structure databases

ProteinModelPortalA9AEY5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9AEY5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5767925.
6359974.
GenomeReviewsGene locus BMULJ_02750 in contig AP009385_GR.
Gene locus Bmul_0510 in contig CP000868_GR.
KEGGbmj:BMULJ_02750.
bmu:Bmul_0510.
PATRIC19167436. VBIBurMul203716_3768.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646350.
OMAMRGELND.
ProtClustDBPRK05387.

Family and domain databases

HAMAPMF_01023. HisC_aminotrans_2.
[Tree]
InterProIPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00817.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. HisC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA9AEY5_BURM1
AccessionPrimary (citable) accession number: A9AEY5
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info