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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR444158:G1GAE-1672-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:MmarC6_1633
OrganismiMethanococcus maripaludis (strain C6 / ATCC BAA-1332)
Taxonomic identifieri444158 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000000791 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953801 – 566Arginine--tRNA ligaseAdd BLAST566

Interactioni

Protein-protein interaction databases

STRINGi444158.MmarC6_1633

Structurei

3D structure databases

ProteinModelPortaliA9AAS2
SMRiA9AAS2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi121 – 131"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00487 Archaea
COG0018 LUCA
HOGENOMiHOG000247213
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG093Z013U

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A9AAS2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVENLIITT LKDKVKELTG TEMDIRLEEP PAINMGDYST NISFRLAKDL
60 70 80 90 100
KKAPKMIAED IANSLSISGI ERIEAVNGYI NFFMNYPDFS KETVSKITSE
110 120 130 140 150
KENFGKLEKR GEKVILEHTS ANPNGPFHIG HGRNMVIGDS LKRILIASGY
160 170 180 190 200
DVETQYYVND MGRQEAIVVF GNERFELDKS KKADHAIGEV YVETNKLLAE
210 220 230 240 250
NEELEQEILN LMKNYESACE AGIENELTEK FKNAVDYSLG GFKETLSTLN
260 270 280 290 300
IYHDKFVWES EFVKSGMVRD VIKRLMDTGK VVEDEVFRLD LSDYGLEKKL
310 320 330 340 350
VLARLNGTSL YSTRDIAYHI NKMENCDFAV NLLGADHKLT AVLVNKTLAL
360 370 380 390 400
LGYNEAEVVF YEFISLPEGS MSTRRGRFIS MDELFEEAKS RAAEEVRKRG
410 420 430 440 450
VAQSEEEIEE IAKKIAVGAV RYNIVRIAPE KPMVFRWDEA LDFEKVGCPV
460 470 480 490 500
IQYAHARCSR ILENVENISN DNLFAYEMNE NEKTIVKLLS KLPKIVEKAA
510 520 530 540 550
EVRKPQIVAN YVLDVAQGFN KFYANCPVLK EENETIKNSR LAIVSTTKTV
560
LENTLDLLGI EMPGKM
Length:566
Mass (Da):64,157
Last modified:January 15, 2008 - v1
Checksum:i3B1013A5FC3AB8EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000867 Genomic DNA Translation: ABX02445.1
RefSeqiWP_012194360.1, NC_009975.1

Genome annotation databases

EnsemblBacteriaiABX02445; ABX02445; MmarC6_1633
GeneIDi5737591
KEGGimmx:MmarC6_1633

Similar proteinsi

Entry informationi

Entry nameiSYR_METM6
AccessioniPrimary (citable) accession number: A9AAS2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 15, 2008
Last modified: February 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome