Skip Header

Contribute Send feedback
Read comments (?) or add your own

A9AAA7 (AROA_METM6) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:MmarC6_1467
OrganismMethanococcus maripaludis (strain C6 / ATCC BAA-1332) [Complete proteome] [HAMAP]
Taxonomic identifier444158 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length429 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 429429Probable 3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099718

Sequences

Sequence LengthMass (Da)Tools
A9AAA7 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 327230EFE825BCDE

FASTA42946,773
        10         20         30         40         50         60 
MLVVKKTPKI NGILNAPPSK SYTHRAVICA SLANGLSNLK NPLNGADCLS SAHACEMFGA 

        70         80         90        100        110        120 
EIELSDEQWV IRGSELKTPD NIVDIGNSGT TLRILTGISS QISNGYTILT GDDSIRKRPM 

       130        140        150        160        170        180 
QPLLDALKQL GIESFSTKNN GTAPIVVKSG KISNNVVEIR GDMSSQFITS LMMTLPFSEN 

       190        200        210        220        230        240 
DSKIVLTTPL KSEPYLNITI DVLDKFGVKI EKNEEKNKLG YKIKGNQRYS PCEYIIEGDY 

       250        260        270        280        290        300 
SSASYLVAAG VLLNSDIVIK NVFKNSKQGD REIIEIVKKM GADVEINEDN VKITGPYNLK 

       310        320        330        340        350        360 
GIEIDVTDIP DLVPTIAVLG CFAEGKTVVY NGEHVRIKEC DRLAACTLEL SKMGAEIEEK 

       370        380        390        400        410        420 
KDGLIITGVH KLNGAKLKTY HDHRLVMAFT IAGMLADGET IIEGEDSVKI SFPDFVDKMK 


SIGSNIEVI

« Hide

References

[1]"Complete sequence of Methanococcus maripaludis C6."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C6 / ATCC BAA-1332.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000867 Genomic DNA. Translation: ABX02280.1.
RefSeqYP_001549512.1. NC_009975.1.

3D structure databases

ProteinModelPortalA9AAA7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9AAA7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5737753.
GenomeReviewsGene locus MmarC6_1467 in contig CP000867_GR.
KEGGmmx:MmarC6_1467.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMARLRIKEC.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycMMAR444158:MMARC6_1467-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_METM6
AccessionPrimary (citable) accession number: A9AAA7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 15, 2008
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents