Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A9AA59

- PUR5_METM6

UniProt

A9AA59 - PUR5_METM6

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (15 Jan 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Purine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMMAR444158:GHN2-1465-MONOMER.
    UniPathwayiUPA00074; UER00129.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
    Alternative name(s):
    AIR synthaseUniRule annotation
    AIRSUniRule annotation
    Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
    Gene namesi
    Name:purMUniRule annotation
    Ordered Locus Names:MmarC6_1419
    OrganismiMethanococcus maripaludis (strain C6 / ATCC BAA-1332)
    Taxonomic identifieri444158 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
    ProteomesiUP000000791: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 349349Phosphoribosylformylglycinamidine cyclo-ligasePRO_1000193061Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi444158.MmarC6_1419.

    Structurei

    3D structure databases

    ProteinModelPortaliA9AA59.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIR synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0150.
    HOGENOMiHOG000229091.
    KOiK01933.
    OMAiVIGKIEH.

    Family and domain databases

    Gene3Di3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPiMF_00741_A. AIRS_A.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsiTIGR00878. purM. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A9AA59-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVTYKDAGVD IYKEDKVIRA LASQIKFERT DAIKPADLKG HYAGAIEFGD    50
    YYLVLCTDGV GSKMVVAEMA NKFDTVPIDM IAMNVNDAIC IGAEPVALVD 100
    YMAVEDITED IASQIGKGLN DGIKESNINL IGGETASLPN MIKGVDLAGT 150
    VLAVVKKDEI VSGKEVKPGD VIVGLRSSGI HSNGLSLARK VFFDITNLDV 200
    NSKLSHGKTV AEELLTPTKI YVKPVLEMIK QVNVKGLAHI TGGGFRKLKR 250
    LNKDVCYKID ELPEILPIFK EIQNLGNVAD QEMFKTFNMG IGFCVIVEKE 300
    DAEKIIEIAN HHNIPAFVIG KIEDSVEIGG KTKRETVLVE YNNKKMIME 349
    Length:349
    Mass (Da):38,145
    Last modified:January 15, 2008 - v1
    Checksum:i26903857D566BAB5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000867 Genomic DNA. Translation: ABX02232.1.
    RefSeqiYP_001549464.1. NC_009975.1.

    Genome annotation databases

    EnsemblBacteriaiABX02232; ABX02232; MmarC6_1419.
    GeneIDi5739143.
    KEGGimmx:MmarC6_1419.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000867 Genomic DNA. Translation: ABX02232.1 .
    RefSeqi YP_001549464.1. NC_009975.1.

    3D structure databases

    ProteinModelPortali A9AA59.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 444158.MmarC6_1419.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABX02232 ; ABX02232 ; MmarC6_1419 .
    GeneIDi 5739143.
    KEGGi mmx:MmarC6_1419.

    Phylogenomic databases

    eggNOGi COG0150.
    HOGENOMi HOG000229091.
    KOi K01933.
    OMAi VIGKIEH.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00129 .
    BioCyci MMAR444158:GHN2-1465-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPi MF_00741_A. AIRS_A.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsi TIGR00878. purM. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C6 / ATCC BAA-1332.

    Entry informationi

    Entry nameiPUR5_METM6
    AccessioniPrimary (citable) accession number: A9AA59
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3