A9A9N7 (DCD_METM6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	MmarC6_1247

Organism

Methanococcus maripaludis (strain C6 / ATCC BAA-1332) [Complete proteome] [HAMAP]

Taxonomic identifier

444158 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 206	206	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000096438

Sequences

	Sequence		Length	Mass (Da)
	A9A9N7 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 700C1C02779D5806	FASTA	206	23,485
	10 20 30 40 50 60 MILSDKDIFD YVNSKRVLIE PFNSKFVGPC SYDVTLGSEF IKYKDDVYDL KKNLSHNKFE 70 80 90 100 110 120 IENSIMVCPL NHHLDETIIE NYKEKYNVDC VVSGGLLGTT NEYVELPNDV CAQYQGRSSF 130 140 150 160 170 180 GRVFLQTHQT AGWIDSGFKG KITLEIVAYD KPVILYKNQR VGQLIFSKTL SPADIGYSDR 190 200 KCSKYAGQKS VMASLIKKDF EIDEEE

References

[1]

"Complete sequence of Methanococcus maripaludis C6." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C6 / ATCC BAA-1332.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000867 Genomic DNA. Translation: ABX02060.1.
RefSeq	YP_001549292.1. NC_009975.1.
3D structure databases
ProteinModelPortal	A9A9N7.
SMR	A9A9N7. Positions 1-199.
ModBase	Search...
Protein-protein interaction databases
STRING	A9A9N7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5738140.
GenomeReviews	Gene locus MmarC6_1247 in contig CP000867_GR.
KEGG	mmx:MmarC6_1247.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553199.
OMA	HQTAGWI.
ProtClustDB	CLSK876187.
Enzyme and pathway databases
BioCyc	MMAR444158:MMARC6_1247-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K09887.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_METM6

Accession

Primary (citable) accession number: A9A9N7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	January 15, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program