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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei155GTPUniRule annotation1
Binding sitei158GTPUniRule annotation1
Binding sitei201GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 41GTPUniRule annotation5
Nucleotide bindingi124 – 126GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR444158:G1GAE-1208-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:MmarC6_1174Imported
OrganismiMethanococcus maripaludis (strain C6 / ATCC BAA-1332)Imported
Taxonomic identifieri444158 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000000791 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Protein-protein interaction databases

STRINGi444158.MmarC6_1174

Structurei

3D structure databases

ProteinModelPortaliA9A9G4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 219TubulinInterPro annotationAdd BLAST191
Domaini221 – 341Tubulin_CInterPro annotationAdd BLAST121

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02201 Archaea
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiIMNQGGV
OrthoDBiPOG093Z0942

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

A9A9G4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLVKEALSK NNEELYNTQM SKEDFGNAKI LVVGCGGAGN NTIHRLSEIG
60 70 80 90 100
IEGAETIAIN TDKQHLEHIN ADKKILIGST LTRGLGAGGY PEIGKKSAEL
110 120 130 140 150
AKNVLEDVIK SADLIFVSAG MGGGTGTGSA PVVAEIAKEN GAVVIGVVTY
160 170 180 190 200
PFKIERARLK KADEGLRRLT ESCDTVIVID NNRLVDFVPN LPMNEAFRVA
210 220 230 240 250
DEIIAQAVKG ITETISLKSL INIDYADVKA VMTNGGVAMI GVGEVDFDTK
260 270 280 290 300
GDRVDKVVKD TLQCPLLDID YKGATGALIH ITGGPDLTLG EANRIGEGIT
310 320 330 340 350
SSMDINANVI WGARLDPSMD GAIRVMAIIT GVKSPNIMGG GRSPAKIIPS
360
SANRSKGSLG IDYIV
Length:365
Mass (Da):38,469
Last modified:January 15, 2008 - v1
Checksum:iB82333F00D867337
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000867 Genomic DNA Translation: ABX01987.1
RefSeqiWP_012193927.1, NC_009975.1

Genome annotation databases

EnsemblBacteriaiABX01987; ABX01987; MmarC6_1174
GeneIDi5738375
KEGGimmx:MmarC6_1174

Similar proteinsi

Entry informationi

Entry nameiA9A9G4_METM6
AccessioniPrimary (citable) accession number: A9A9G4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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