Reviewed, UniProtKB/Swiss-Prot A9A979 (PDAD_METM6)

Names and origin

Protein names

Recommended name:
    Pyruvoyl-dependent arginine decarboxylase
      Short name=PvlArgDC
    EC=4.1.1.19
Cleaved into the following 2 chains:
    1- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit beta
    2- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit alpha

Gene names

Name:	pdaD
Ordered Locus Names:	MmarC6_1088

Organism

Methanococcus maripaludis (strain C6 / ATCC BAA-1332) [Complete proteome] [HAMAP]

Taxonomic identifier

444158 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	164 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2. HAMAP MF_01404
Cofactor	Pyruvoyl group By similarity.
Sequence similarities	Belongs to the pdaD family.

Ontologies

Keywords
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 51	51	Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity		PRO_1000145470
	Chain	52 – 164	113	Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity		PRO_1000145471
Sites
	Site	51 – 52	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	52	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9A979-1 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: E03A3FA47FEDC183	FASTA	164	17,631
	10 20 30 40 50 60 MMKTSAIHSP FEAPNTISLV AGTGDAKNPL NAFDMSLLES GIGNLNLIRI SSIMPPKADI 70 80 90 100 110 120 IPLPKIPQGS LVPTAYGYQI SELKGETVAA GISVAIPKDK ELCGLIMEYE CIGGKKECED 130 140 150 160 TVRNMAKEGF EMRGWEIDEI ISIASEHTVE NIGCAFAAAA LWYK

References

[1]

"Complete sequence of Methanococcus maripaludis C6." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000867 Genomic DNA. Translation: ABX01902.1.
RefSeq	YP_001549134.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5738080.
GenomeReviews	Gene locus MmarC6_1088 in contig CP000867_GR.
KEGG	mmx:MmarC6_1088.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	LVPTAYG.
Family and domain databases
HAMAP	MF_01404. [Tree]
InterPro	IPR002724. Pyruvoyl-dep_arg_deCO2ase. [Graphical view]
Pfam	PF01862. PvlArgDC. 1 hit. [Graphical view]
PIRSF	PIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDom	PD010449. DUF44. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00286. PvlArgDC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PDAD_METM6

Accession

Primary (citable) accession number: A9A979

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	January 15, 2008
Last modified:	November 3, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)