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Protein

DNA polymerase sliding clamp

Gene

pcn

Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Enzyme and pathway databases

BioCyciMMAR444158:G1GAE-984-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clampUniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homologUniRule annotation
Short name:
PCNAUniRule annotation
Gene namesi
Name:pcnUniRule annotation
Ordered Locus Names:MmarC6_0960
OrganismiMethanococcus maripaludis (strain C6 / ATCC BAA-1332)
Taxonomic identifieri444158 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000000791 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001158151 – 250DNA polymerase sliding clampAdd BLAST250

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Protein-protein interaction databases

STRINGi444158.MmarC6_0960

Structurei

3D structure databases

ProteinModelPortaliA9A8V2
SMRiA9A8V2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
HOGENOMiHOG000222371
KOiK04802
OMAiKCANSDD
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN
TIGRFAMsiTIGR00590 pcna, 1 hit
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit

Sequencei

Sequence statusi: Complete.

A9A8V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRATCNTRD FKKVINATSN LVDEICFEVD ENGIKASAMD PSHVALVSME
60 70 80 90 100
MPKEVFEEYE GDIHDIGIDL EALKKIIARG KGDEKLILDL DVEKNKLNVT
110 120 130 140 150
FKSNVTRKFS IALYDVSSSN LKVPDIEYPN NVSIKAGAFV EALKDAELVN
160 170 180 190 200
DHITLKVDED KFIIYSKGDL NQSETVFDNG IEDDDATLAE FNMGEASRST
210 220 230 240 250
FNLAYLKDLT KSTAAEDLLK IYLGSDMPVK IEYEVSGSKL VFLLAPRIES
Length:250
Mass (Da):27,865
Last modified:January 15, 2008 - v1
Checksum:iE2F31E8DB878F0C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000867 Genomic DNA Translation: ABX01775.1
RefSeqiWP_012193725.1, NC_009975.1

Genome annotation databases

EnsemblBacteriaiABX01775; ABX01775; MmarC6_0960
GeneIDi5738457
KEGGimmx:MmarC6_0960

Similar proteinsi

Entry informationi

Entry nameiPCNA_METM6
AccessioniPrimary (citable) accession number: A9A8V2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 15, 2008
Last modified: March 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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