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A9A813

- IF2P_METM6

UniProt

A9A813 - IF2P_METM6

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Protein
Probable translation initiation factor IF-2
Gene
infB, MmarC6_0669
Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 198GTP By similarity
Nucleotide bindingi76 – 805GTP By similarity
Nucleotide bindingi130 – 1334GTP By similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-KW
  2. GTPase activity Source: UniProtKB-HAMAP
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR444158:GHN2-677-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable translation initiation factor IF-2
Gene namesi
Name:infB
Ordered Locus Names:MmarC6_0669
OrganismiMethanococcus maripaludis (strain C6 / ATCC BAA-1332)
Taxonomic identifieri444158 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
ProteomesiUP000000791: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 598598Probable translation initiation factor IF-2UniRule annotation
PRO_1000093802Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi444158.MmarC6_0669.

Structurei

3D structure databases

ProteinModelPortaliA9A813.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 225223tr-type G
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni12 – 198G1 By similarity
Regioni37 – 415G2 By similarity
Regioni76 – 794G3 By similarity
Regioni130 – 1334G4 By similarity
Regioni200 – 2023G5 By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000105770.
KOiK03243.
OMAiIVCVMGH.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_A. IF_2_A.
InterProiIPR000795. EF_GTP-bd_dom.
IPR029459. EFTU-type.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR004544. TIF_aIF-2_arc.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF14578. GTP_EFTU_D4. 1 hit.
PF11987. IF-2. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00491. aIF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9A813-1 [UniParc]FASTAAdd to Basket

« Hide

MALRCPIVSV LGHVDHGKTS LLDKIRSTRV TQREAGGITQ HIGASEIPIN    50
TIKKVSKDLL GLFKADLTIP GLLVIDTPGH EAFTSLRKRG GALADIAILV 100
VDMNEGFKPQ TIEAINILKQ CKTPFIVAAN KLDRVPGWNS KEGPFILNFN 150
EKNQHPNAMT EFEIRLYENV IKHLNELGFD ADLFSRVKDT TKTINVVPVS 200
AMTGEGIPDL LVIISGLAQK FLEQKLALNV EGYAKGTVLE LKEEKGLGKT 250
IDAIIYDGIA KTGDFLVVGN PQGVLVSKIK ALLKPKELDE MRDPKDKFKP 300
SKQISAATGV KISAPDLDNV IAGSPLRIVP KDQIENAKAE VLQEVEEFTI 350
LTDDEGIIIK ADTMGSLEAL ANELRKVKAK IKKAEVGDIS KKDVIEASSY 400
ASTNPLNGLI ISFNTKVLSD AKAEIEKSDV KLLEGRIIYK LVEEYEEWVK 450
EMEELMKSDE INRLTKPAMI KILPNCIFRQ KEPAVCGVEV LYGTLKIGSP 500
LMSEDGKKLG YVKEIRDNQQ ENIKEAKVGM QVPVSIDGNI VLGRNAKEND 550
ILYVEVPEPE ARKLHHEFRD ELRGDEKEAL SRYMELKQKI ENNIFWGM 598
Length:598
Mass (Da):66,289
Last modified:January 15, 2008 - v1
Checksum:iA848923E8956D0D7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000867 Genomic DNA. Translation: ABX01486.1.
RefSeqiWP_012193384.1. NC_009975.1.
YP_001548718.1. NC_009975.1.

Genome annotation databases

EnsemblBacteriaiABX01486; ABX01486; MmarC6_0669.
GeneIDi5738967.
KEGGimmx:MmarC6_0669.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000867 Genomic DNA. Translation: ABX01486.1 .
RefSeqi WP_012193384.1. NC_009975.1.
YP_001548718.1. NC_009975.1.

3D structure databases

ProteinModelPortali A9A813.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 444158.MmarC6_0669.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX01486 ; ABX01486 ; MmarC6_0669 .
GeneIDi 5738967.
KEGGi mmx:MmarC6_0669.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000105770.
KOi K03243.
OMAi IVCVMGH.

Enzyme and pathway databases

BioCyci MMAR444158:GHN2-677-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_A. IF_2_A.
InterProi IPR000795. EF_GTP-bd_dom.
IPR029459. EFTU-type.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR004544. TIF_aIF-2_arc.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF14578. GTP_EFTU_D4. 1 hit.
PF11987. IF-2. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00491. aIF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C6 / ATCC BAA-1332.

Entry informationi

Entry nameiIF2P_METM6
AccessioniPrimary (citable) accession number: A9A813
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 15, 2008
Last modified: September 3, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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