Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable translation initiation factor IF-2

Gene

infB

Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19GTPUniRule annotation8
Nucleotide bindingi76 – 80GTPUniRule annotation5
Nucleotide bindingi130 – 133GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR444158:G1GAE-672-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable translation initiation factor IF-2UniRule annotation
Gene namesi
Name:infBUniRule annotation
Ordered Locus Names:MmarC6_0669
OrganismiMethanococcus maripaludis (strain C6 / ATCC BAA-1332)
Taxonomic identifieri444158 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000000791 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000938021 – 598Probable translation initiation factor IF-2Add BLAST598

Proteomic databases

PRIDEiA9A813

Interactioni

Protein-protein interaction databases

STRINGi444158.MmarC6_0669

Structurei

3D structure databases

ProteinModelPortaliA9A813
SMRiA9A813
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 225tr-type GAdd BLAST223

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni12 – 19G1By similarity8
Regioni37 – 41G2By similarity5
Regioni76 – 79G3By similarity4
Regioni130 – 133G4By similarity4
Regioni200 – 202G5By similarity3

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01560 Archaea
COG0532 LUCA
HOGENOMiHOG000105770
KOiK03243
OMAiFRQSKPA
OrthoDBiPOG093Z012A

Family and domain databases

Gene3Di3.40.50.10050, 1 hit
HAMAPiMF_00100_A IF_2_A, 1 hit
InterProiView protein in InterPro
IPR029459 EFTU-type
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR004544 TIF_aIF-2_arc
IPR015760 TIF_IF2
IPR023115 TIF_IF2_dom3
IPR036925 TIF_IF2_dom3_sf
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR43381 PTHR43381, 1 hit
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF14578 GTP_EFTU_D4, 1 hit
PF11987 IF-2, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF52156 SSF52156, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00491 aIF-2, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

A9A813-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALRCPIVSV LGHVDHGKTS LLDKIRSTRV TQREAGGITQ HIGASEIPIN
60 70 80 90 100
TIKKVSKDLL GLFKADLTIP GLLVIDTPGH EAFTSLRKRG GALADIAILV
110 120 130 140 150
VDMNEGFKPQ TIEAINILKQ CKTPFIVAAN KLDRVPGWNS KEGPFILNFN
160 170 180 190 200
EKNQHPNAMT EFEIRLYENV IKHLNELGFD ADLFSRVKDT TKTINVVPVS
210 220 230 240 250
AMTGEGIPDL LVIISGLAQK FLEQKLALNV EGYAKGTVLE LKEEKGLGKT
260 270 280 290 300
IDAIIYDGIA KTGDFLVVGN PQGVLVSKIK ALLKPKELDE MRDPKDKFKP
310 320 330 340 350
SKQISAATGV KISAPDLDNV IAGSPLRIVP KDQIENAKAE VLQEVEEFTI
360 370 380 390 400
LTDDEGIIIK ADTMGSLEAL ANELRKVKAK IKKAEVGDIS KKDVIEASSY
410 420 430 440 450
ASTNPLNGLI ISFNTKVLSD AKAEIEKSDV KLLEGRIIYK LVEEYEEWVK
460 470 480 490 500
EMEELMKSDE INRLTKPAMI KILPNCIFRQ KEPAVCGVEV LYGTLKIGSP
510 520 530 540 550
LMSEDGKKLG YVKEIRDNQQ ENIKEAKVGM QVPVSIDGNI VLGRNAKEND
560 570 580 590
ILYVEVPEPE ARKLHHEFRD ELRGDEKEAL SRYMELKQKI ENNIFWGM
Length:598
Mass (Da):66,289
Last modified:January 15, 2008 - v1
Checksum:iA848923E8956D0D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000867 Genomic DNA Translation: ABX01486.1
RefSeqiWP_012193384.1, NC_009975.1

Genome annotation databases

EnsemblBacteriaiABX01486; ABX01486; MmarC6_0669
GeneIDi5738967
KEGGimmx:MmarC6_0669

Similar proteinsi

Entry informationi

Entry nameiIF2P_METM6
AccessioniPrimary (citable) accession number: A9A813
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 15, 2008
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health