A9A7C4 (A9A7C4_METM6) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Adenine phosphoribosyltransferase 1 HAMAP MF_00004
Short name=APRT 1 HAMAP MF_00004
EC=2.4.2.7 HAMAP MF_00004

Gene names

Name:	apt1 HAMAP MF_00004
Ordered Locus Names:	MmarC6_0227

Organism

Methanococcus maripaludis (strain C6 / ATCC BAA-1332) [Complete proteome] [HAMAP]

Taxonomic identifier

444158 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	172 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis By similarity. HAMAP MF_00004
Catalytic activity	AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00004
Pathway	Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1. HAMAP MF_00004
Subunit structure	Homodimer By similarity. HAMAP MF_00004
Subcellular location	Cytoplasm By similarity HAMAP MF_00004.
Sequence similarities	Belongs to the purine/pyrimidine phosphoribosyltransferase family. HAMAP MF_00004

Ontologies

Keywords
Biological process	Purine salvage HAMAP MF_00004
Cellular component	Cytoplasm HAMAP MF_00004
Molecular function	Glycosyltransferase HAMAP MF_00004 EMBL ABX01048.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	adenine salvage Inferred from electronic annotation. Source: HAMAP purine ribonucleoside salvage Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	adenine phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9A7C4 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: C5047660D5F738BA	FASTA	172	19,051
	10 20 30 40 50 60 MDLRKKIRIV ENFPIEGISF KDVTPILKDP KAMKHTTKEI TKYLEDKNVD LIVGPEARGF 70 80 90 100 110 120 LFGIPVAHEL DIGFVPVRKP GKLPYKTFSV DYALEYGADS LEIHSDGLEK GQNVAIVDDL 130 140 150 160 170 LATGGTVLGV SKLVEKLGGH ISALNFVIEL TELKGRDKLK GYNIQSLVKY DL

References

[1]

"Complete sequence of Methanococcus maripaludis C6." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C6 / ATCC BAA-1332.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000867 Genomic DNA. Translation: ABX01048.1.
RefSeq	YP_001548280.1. NC_009975.1.
3D structure databases
ProteinModelPortal	A9A7C4.
ModBase	Search...
Protein-protein interaction databases
STRING	A9A7C4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5738705.
GenomeReviews	Gene locus MmarC6_0227 in contig CP000867_GR.
KEGG	mmx:MmarC6_0227.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG703830.
OMA	MNAACEL.
ProtClustDB	PRK12560.
Family and domain databases
HAMAP	MF_00004. Aden_phosphoribosyltr. [Tree]
InterPro	IPR005764. Ade_phspho_trans. IPR000836. PRibTrfase. [Graphical view]
KO	K00759.
Pfam	PF00156. Pribosyltran. 1 hit. [Graphical view]
TIGRFAMs	TIGR01090. Apt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9A7C4_METM6

Accession

Primary (citable) accession number: A9A7C4

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	November 16, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)