A9A5X8 (A9A5X8_NITMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydroxymethylglutaryl-CoA reductase, degradative EMBL ABX13456.1
EC=1.1.1.88 EMBL ABX13456.1

Gene names

Ordered Locus Names:

Nmar_1560

Organism

Nitrosopumilus maritimus (strain SCM1)

Taxonomic identifier

436308 [NCBI]

Taxonomic lineage

Archaea › Thaumarchaeota › marine archaeal group 1 › Nitrosopumilales › Nitrosopumilaceae › Nitrosopumilus

Protein attributes

Sequence length	418 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004269 EMBL ABX13456.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9A5X8 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 89C2C92D910E0F04	FASTA	418	44,959
	10 20 30 40 50 60 MPDSSISKFF EKTRTERLDV IKNFANLSED DVKSLELPDG GITFDKADKM VENAFGTFSL 70 80 90 100 110 120 PLGVATNFKI NNKDYLVPMV IEEPSVIAAA SKAAKLARPK GGFAVVADES YSIGQIQVLG 130 140 150 160 170 180 TDIDNAISKI KENIKEILEL ANSKSNTLSK MGKGAKEITC KKLDTDFEPM LIVELLIDVG 190 200 210 220 230 240 DAMGANVTNT MCEGVAPLIE KLTSGKTLLR ILSNYSTRRM VKATAVFDKE SVGGEKVVDN 250 260 270 280 290 300 MIHAYQFAKH DVYRAVTHNK GIMNGIIAVA NATGQDSRAI EAAANAYASR SGQYRSLSEW 310 320 330 340 350 360 TKDSDGNLVG TLEIPLSVGI VGGIINVHPV AKICTKILGA ESAKEMACII TATGLAQNFS 370 380 390 400 410 AMRALATDGI QKGHMRLHAR NLASAAGAST EQIDKIVSQM IEENNISVNR AKELLEQN

References

[1]

"Complete sequence of Nitrosopumilus maritimus SCM1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Stahl D., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCM1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000866 Genomic DNA. Translation: ABX13456.1.
RefSeq	YP_001582894.1. NC_010085.1.
3D structure databases
ProteinModelPortal	A9A5X8.
ModBase	Search...
Protein-protein interaction databases
STRING	A9A5X8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5773942.
GenomeReviews	Gene locus Nmar_1560 in contig CP000866_GR.
KEGG	nmr:Nmar_1560.
Phylogenomic databases
HOGENOM	HBG477902.
OMA	NNKGIMN.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR023076. HMG_CoA_Rdtase_CS. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
PANTHER	PTHR10572. HMG-CoA_red. 1 hit.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
PRINTS	PR00071. HMGCOARDTASE.
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS01192. HMG_COA_REDUCTASE_3. 1 hit. PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9A5X8_NITMS

Accession

Primary (citable) accession number: A9A5X8

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	November 16, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)