Reviewed, UniProtKB/Swiss-Prot A9A5S1 (PDAD_NITMS)

Names and origin

Protein names

Recommended name:
    Pyruvoyl-dependent arginine decarboxylase
      Short name=PvlArgDC
    EC=4.1.1.19
Cleaved into the following 2 chains:
    1- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit beta
    2- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit alpha

Gene names

Name:	pdaD
Ordered Locus Names:	Nmar_1180

Organism

Nitrosopumilus maritimus (strain SCM1) [Complete proteome] [HAMAP]

Taxonomic identifier

436308 [NCBI]

Taxonomic lineage

Archaea › Thaumarchaeota › marine archaeal group 1 › Nitrosopumilales › Nitrosopumilaceae › Nitrosopumilus

Protein attributes

Sequence length	183 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2. HAMAP MF_01404
Cofactor	Pyruvoyl group By similarity. HAMAP MF_01404
Sequence similarities	Belongs to the pdaD family.

Ontologies

Keywords
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 43	43	Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity		PRO_1000145472
	Chain	44 – 183	140	Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity		PRO_1000145473
Sites
	Site	43 – 44	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	44	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9A5S1-1 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 0E5D71CB24A68451	FASTA	183	20,507
	10 20 30 40 50 60 MLDLVAKKLF LTRGKGIHED RLTSFEYALR DAGIAGTNLV LISSIFPPKA KLISRKEGLQ 70 80 90 100 110 120 QIKPGQILFT IYSKNQTNEP HRMCSASVGI AQPKDKDRYG YLSEYEAFGQ TETQAGDYAE 130 140 150 160 170 180 DIAAQMLASS LGIPFDVDKN WDEKRQQWKI SGEIYKTQNI TQQTRGDKDG KWTTVFAAAV LLV

References

[1]

"Complete sequence of Nitrosopumilus maritimus SCM1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Stahl D., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000866 Genomic DNA. Translation: ABX13076.1.
RefSeq	YP_001582514.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5773086.
GenomeReviews	Gene locus Nmar_1180 in contig CP000866_GR.
KEGG	nmr:Nmar_1180.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG539680.
OMA	YKMSGKI.
Family and domain databases
HAMAP	MF_01404. PvlArgDC. [Tree]
InterPro	IPR016104. Pyr-dep_his/arg-deCO2ase. IPR002724. Pyruvoyl-dep_arg_deCO2ase. [Graphical view]
Pfam	PF01862. PvlArgDC. 1 hit. [Graphical view]
PIRSF	PIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDom	PD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00286. PvlArgDC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PDAD_NITMS

Accession

Primary (citable) accession number: A9A5S1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	January 15, 2008
Last modified:	February 9, 2010
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)