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A9A5G6 (A9A5G6_NITMS) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Amidophosphoribosyltransferase PIRNR PIRNR000485
Short name=ATase PIRNR PIRNR000485
EC=2.4.2.14 PIRNR PIRNR000485
Alternative name(s):
Glutamine phosphoribosylpyrophosphate amidotransferase PIRNR PIRNR000485
Gene names
Ordered Locus Names:Nmar_0781
OrganismNitrosopumilus maritimus (strain SCM1)
Taxonomic identifier436308 [NCBI]
Taxonomic lineageArchaea › Thaumarchaeota › marine archaeal group 1 › Nitrosopumilales › Nitrosopumilaceae › Nitrosopumilus

Protein attributes

Sequence length489 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O. PIRNR PIRNR000485

Cofactor

Binds 1 4Fe-4S cluster per subunit By similarity. PIRSR PIRSR000485-3

Binds 1 magnesium ion per subunit By similarity. PIRNR PIRNR000485

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2. PIRNR PIRNR000485

Sequence similarities

In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. PIRNR PIRNR000485

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site161For GATase activity By similarity PIRSR PIRSR000485-1
Metal binding2521Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4021Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4611Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4641Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3

Sequences

Sequence LengthMass (Da)Tools
A9A5G6 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 24CEDBD758A00470

FASTA48953,314
        10         20         30         40         50         60 
MDKPQHTLDD KPKENCGVIG IYSLSGANVI PMAIDALRAL QHRGQEAWGL AIPNKPPLKR 

        70         80         90        100        110        120 
LGLVSAASSE FKSIAQEYSS PCVIGHVRYS TMGRSSLENA QPLKVKDLCV AHNGTIANVQ 

       130        140        150        160        170        180 
ELSNLVGGCS FTPQNASDTL VAAQRLVSLI SENGQMGKAL SVLKNEMVGS YCFTFISDDN 

       190        200        210        220        230        240 
SVFAARDPKG FRPMVLGHKE SDDTYIVASE SSAVSAVGAK MQRNVTPGEL IRMSKDGIDT 

       250        260        270        280        290        300 
EMFSDDPKRA HCSFEFTYFA HPTSNMEGTN IYVARKNIGR YLAKKFPIKD ADLVIPVPDS 

       310        320        330        340        350        360 
ARPAALGYAQ ELGVSFDEGL LKDRYSKKGP LRSFIEPHQT DRVEINRWII PIREIIDGKH 

       370        380        390        400        410        420 
VVVIDDSLVR GTSSKAIIKA LRRAGARKIS MVITYPPIKF PCYAGIDFPS QEELATFSNG 

       430        440        450        460        470        480 
KDLNDEETID MVRKDIGADF LGYNDAENLA AAVGIPADSM CFTCASGNYD SLGITPEFKS 


REEIKGEAS

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References

[1]"Complete sequence of Nitrosopumilus maritimus SCM1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Stahl D., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SCM1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000866 Genomic DNA. Translation: ABX12677.1.
RefSeqYP_001582115.1. NC_010085.1.

3D structure databases

ProteinModelPortalA9A5G6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9A5G6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5773545.
GenomeReviewsGene locus Nmar_0781 in contig CP000866_GR.
KEGGnmr:Nmar_0781.

Phylogenomic databases

HOGENOMHBG392416.
OMAVWAPGEE.

Family and domain databases

InterProIPR005854. Amd_phspho_trans.
IPR000583. GATase_2.
IPR017932. GATase_II.
IPR000836. PRibTrfase.
[Graphical view]
KOK00764.
PANTHERPTHR11907. Amd_phspho_trans. 1 hit.
PfamPF00310. GATase_2. 1 hit.
PF00156. Pribosyltran. 1 hit.
[Graphical view]
PIRSFPIRSF000485. Amd_phspho_trans. 1 hit.
PROSITEPS51278. GATASE_TYPE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA9A5G6_NITMS
AccessionPrimary (citable) accession number: A9A5G6
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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