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A9A532 (A9A532_NITMS) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Homoserine kinase HAMAP MF_00384
Short name=HK HAMAP MF_00384
Short name=HSK HAMAP MF_00384
EC=2.7.1.39 HAMAP MF_00384
Gene names
Name:thrB HAMAP MF_00384
Ordered Locus Names:Nmar_0041
OrganismNitrosopumilus maritimus (strain SCM1)
Taxonomic identifier436308 [NCBI]
Taxonomic lineageArchaea › Thaumarchaeota › marine archaeal group 1 › Nitrosopumilales › Nitrosopumilaceae › Nitrosopumilus

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate By similarity. HAMAP MF_00384

Catalytic activity

ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP MF_00384

Pathway

Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP MF_00384

Subcellular location

Cytoplasm By similarity HAMAP MF_00384.

Sequence similarities

Belongs to the GHMP kinase family. RuleBase RU004209

Belongs to the GHMP kinase family. Homoserine kinase subfamily. HAMAP MF_00384

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding86 – 9611ATP By similarity HAMAP MF_00384

Sequences

Sequence LengthMass (Da)Tools
A9A532 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 23EE5702E086EB26

FASTA30732,021
        10         20         30         40         50         60 
MASKVTVKAP SSTANLGPGF DVFGLAVDAF YDEVTLTKTK SRITIVTDDN IPTKPDNNTA 

        70         80         90        100        110        120 
GLVVKNMKKK FKIKSGVEIK IKKGVPAGFG MGSSAASAAA TAVAFDKLFG LKLDGNSLVE 

       130        140        150        160        170        180 
FAGSGEKASA GSVHYDNVAA SVLGGFVIVK TNPLQVTRVD PPTNLRMCVA VPKLEVPKKK 

       190        200        210        220        230        240 
TKVSRGVIPK KVKLTDSILN LSNASAIVAG FMKKDPELIG NSIKDVIVEP ARKHMIPGFD 

       250        260        270        280        290        300 
KVKENALKAG ALGVTISGAG PSVIAFSKSS ADLKKISSAM SRGFASAKTE CQTVICKPSK 


GAADKRR

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References

[1]"Complete sequence of Nitrosopumilus maritimus SCM1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Stahl D., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SCM1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000866 Genomic DNA. Translation: ABX11941.1.
RefSeqYP_001581379.1. NC_010085.1.

3D structure databases

ProteinModelPortalA9A532.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9A532.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5774067.
GenomeReviewsGene locus Nmar_0041 in contig CP000866_GR.
KEGGnmr:Nmar_0041.

Phylogenomic databases

HOGENOMHBG646290.
OMAGSAHADN.

Family and domain databases

HAMAPMF_00384. Homoser_kinase.
[Tree]
InterProIPR006204. GHMP_kinase.
IPR013750. GHMP_kinase_C.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR000870. Homoserine_kinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
Gene3DG3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK00872.
PfamPF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF000676. Homoser_kin. 1 hit.
PRINTSPR00958. HOMSERKINASE.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00191. ThrB. 1 hit.
PROSITEPS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA9A532_NITMS
AccessionPrimary (citable) accession number: A9A532
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: November 16, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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