A9A3F9 (A9A3F9_NITMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401
Ordered Locus Names:	Nmar_0995

Organism

Nitrosopumilus maritimus (strain SCM1)

Taxonomic identifier

436308 [NCBI]

Taxonomic lineage

Archaea › Thaumarchaeota › marine archaeal group 1 › Nitrosopumilales › Nitrosopumilaceae › Nitrosopumilus

Protein attributes

Sequence length	150 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL ABX12891.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	9	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A9A3F9 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 43BFA0D7DD94E38C	FASTA	150	17,106
	10 20 30 40 50 60 MKATFGAGCF WHVEDLLSKT KGVKSTQVGY IGGNLPNPTY EEVCTDRTGH AEAVEVEYDP 70 80 90 100 110 120 NEISYEELLD VFWNNHNPTT LNRQGPDVGI QYRSAIFYHD EKQKEVAEKS KTQLDSSGKF 130 140 150 NDPIVTEITP APTFYKAEEY HQKYFKKNGF

References

[1]

"Complete sequence of Nitrosopumilus maritimus SCM1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Stahl D., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCM1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000866 Genomic DNA. Translation: ABX12891.1.
RefSeq	YP_001582329.1. NC_010085.1.
3D structure databases
ProteinModelPortal	A9A3F9.
SMR	A9A3F9. Positions 2-149.
ModBase	Search...
Protein-protein interaction databases
STRING	A9A3F9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5773137.
GenomeReviews	Gene locus Nmar_0995 in contig CP000866_GR.
KEGG	nmr:Nmar_0995.
Phylogenomic databases
HOGENOM	HBG748152.
OMA	FILAGGC.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9A3F9_NITMS

Accession

Primary (citable) accession number: A9A3F9

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	November 16, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)