Reviewed, UniProtKB/Swiss-Prot A9A0L5 (SYGA_DESOH)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	Dole_1711

Organism

Desulfococcus oleovorans (strain DSM 6200 / Hxd3) [Complete proteome] [HAMAP]

Taxonomic identifier

96561 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfobacterales › Desulfobacteraceae › Desulfococcus

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 300	300	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000197177

Sequences

	Sequence		Length	Mass (Da)
	A9A0L5-1 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: A2F72A71C2E86A0E	FASTA	300	34,408
	10 20 30 40 50 60 MNGTMNFQEI ILNLQRFWAK KGCVLVQPYD MEVGAGTFHP ETLLRALGPE PWQVAYVQPS 70 80 90 100 110 120 RRPTDGRYGE NPNRLQHYYQ FQVMLKPSPG NVQQLYLKSL ATLGIFASDH DIRFVEDDWE 130 140 150 160 170 180 SPTLGASGLG WEVWLDGMEI TQFTYFQAAG SIDLSPVSVE ITYGLERIAM YMQGINNVYD 190 200 210 220 230 240 LVWRDHITYG HLHHRQEVEQ SAYNFEHADV EMLFDCFGKY EHEAGRMIAE SLVLPAYEYC 250 260 270 280 290 300 LKCSHTFNLL DARGAISVTE RTGYIKRIRD IARACATTYL QQREEMGFPL LNAGHRGTTE

References

[1]

"Complete sequence of Desulfococcus oleovorans Hxd3." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Wawrik B., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000859 Genomic DNA. Translation: ABW67515.1.
RefSeq	YP_001529592.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5694549.
GenomeReviews	Gene locus Dole_1711 in contig CP000859_GR.
KEGG	dol:Dole_1711.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CRRPTDG.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
ProDom	PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_DESOH

Accession

Primary (citable) accession number: A9A0L5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	January 15, 2008
Last modified:	November 3, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)