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A8ZYU4 (A8ZYU4_DESOH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP MF_00186
Glycerokinase HAMAP MF_00186
Gene names
Name:glpK HAMAP MF_00186
Ordered Locus Names:Dole_1395
OrganismDesulfococcus oleovorans (strain DSM 6200 / Hxd3) [Complete proteome] [HAMAP]
Taxonomic identifier96561 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfobacterales › Desulfobacteraceae › Desulfococcus

Protein attributes

Sequence length505 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186 SAAS SAAS018483

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186 SAAS SAAS018483

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186 SAAS SAAS018483

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding416 – 4205ATP By similarity HAMAP MF_00186

Sites

Binding site141Substrate By similarity HAMAP MF_00186
Binding site181ATP By similarity HAMAP MF_00186
Binding site841Substrate By similarity HAMAP MF_00186
Binding site1361Substrate By similarity HAMAP MF_00186
Binding site2491Substrate By similarity HAMAP MF_00186
Binding site2711ATP By similarity HAMAP MF_00186
Binding site3151ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
A8ZYU4 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: DD4A5F50CBCD26A3

FASTA50555,168
        10         20         30         40         50         60 
MTDKQYVGAI DQGTTSTRFV VFDTTGAMVA SHQVEHRQIY PEPGFVEHDP MEIRANTAGI 

        70         80         90        100        110        120 
IAEALKKGLI EPDQIAAVGI TNQRETTVVW NRHTGRPLYN AIVWQDTRTA DMCTALKQEG 

       130        140        150        160        170        180 
HEPLFKEKTG LPAASYFSGP KIRWILDNVE GARAAAEKGD ALFGNMDTWL IWWLTGGPGK 

       190        200        210        220        230        240 
GVHVTDVTNA SRTMLMNLET LAWDSELLKI LDIPEKMLPR IMASSEVYGH AAQNWGLAPG 

       250        260        270        280        290        300 
TPVSGDLGDQ QAALFGQVCF EPGEAKNTYG TGCFLLSNTG QKIIHSNHGL LTTLGYKIGN 

       310        320        330        340        350        360 
EPPVYALEGS VAVAGSLVQW LRDNLNLIRT SPEVEDLAKT VADNGGVYFV PAFSGLFAPH 

       370        380        390        400        410        420 
WDSSARGLII GMTHYINKGH IARAALESTA FQVNEIFSAM EKDSGIPFKS LKVDGGMAAN 

       430        440        450        460        470        480 
DLLMQFQADL VRVPVIRSAV LESTVLGAAY AAGLAVGFWS KKEDLRRHWK ENGQWQPEMA 

       490        500 
AALRDKMCAQ WDKAIKRAAG WKEEG

« Hide

References

[1]"Complete sequence of Desulfococcus oleovorans Hxd3."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Wawrik B., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 6200 / Hxd3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000859 Genomic DNA. Translation: ABW67199.1.
RefSeqYP_001529276.1. NC_009943.1.

3D structure databases

ProteinModelPortalA8ZYU4.
SMRA8ZYU4. Positions 5-504.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8ZYU4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5694230.
GenomeReviewsGene locus Dole_1395 in contig CP000859_GR.
KEGGdol:Dole_1395.
PATRIC21692863. VBIDesOle35880_1441.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG511469.
OMAATYFSGT.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8ZYU4_DESOH
AccessionPrimary (citable) accession number: A8ZYU4
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info