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A8ZXS5

- A8ZXS5_DESOH

UniProt

A8ZXS5 - A8ZXS5_DESOH

Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

Dole_2749

Organism
Desulfococcus oleovorans (strain DSM 6200 / Hxd3)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (15 Jan 2008)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciDOLE96561:GHF3-2791-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
    Gene namesi
    Ordered Locus Names:Dole_2749Imported
    OrganismiDesulfococcus oleovorans (strain DSM 6200 / Hxd3)Imported
    Taxonomic identifieri96561 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobacteraceaeDesulfococcus
    ProteomesiUP000008561: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi96561.Dole_2749.

    Structurei

    3D structure databases

    ProteinModelPortaliA8ZXS5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG1181.
    KOiK01921.
    OMAiIKCPMEV.
    OrthoDBiEOG66MQKK.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8ZXS5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLAFLYNVR HQYPDPDRPE TQVEADFDDP ETIAAMTAHL RECGFDVIPI    50
    EADPDAYIKL YENRDSIDLV FNYSIGIYGQ ARYAQVPAML EMLRLPYTGS 100
    GPLTQALILD KARMQQVLSA CNVPVLCSQV FETGDEPLQS GLAFPLIVKP 150
    VAQGSSAGIT SDSVVRDEAA LYRQVGRVMA TFGEPALVQP FLDGREFSIP 200
    MMGNPPEIFP IIEPDFSRLP EGYARIDSLE VKWIFEEQAE SHHLICPAPV 250
    APGLQERLEQ TVRAAWKALG ICDWCRIDLR CDMAGTPYVI DVNSPPGMIP 300
    PEGSMTSYFP MSARAAGIDY QGLLKRLIET AMDRLSAR 338
    Length:338
    Mass (Da):37,520
    Last modified:January 15, 2008 - v1
    Checksum:i66429646D86096C7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000859 Genomic DNA. Translation: ABW68552.1.
    RefSeqiYP_001530629.1. NC_009943.1.

    Genome annotation databases

    EnsemblBacteriaiABW68552; ABW68552; Dole_2749.
    GeneIDi5695605.
    KEGGidol:Dole_2749.
    PATRICi21695669. VBIDesOle35880_2824.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000859 Genomic DNA. Translation: ABW68552.1 .
    RefSeqi YP_001530629.1. NC_009943.1.

    3D structure databases

    ProteinModelPortali A8ZXS5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 96561.Dole_2749.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABW68552 ; ABW68552 ; Dole_2749 .
    GeneIDi 5695605.
    KEGGi dol:Dole_2749.
    PATRICi 21695669. VBIDesOle35880_2824.

    Phylogenomic databases

    eggNOGi COG1181.
    KOi K01921.
    OMAi IKCPMEV.
    OrthoDBi EOG66MQKK.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci DOLE96561:GHF3-2791-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 6200 / Hxd3Imported.

    Entry informationi

    Entry nameiA8ZXS5_DESOH
    AccessioniPrimary (citable) accession number: A8ZXS5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 15, 2008
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3