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A8ZUH0 (A8ZUH0_DESOH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818
EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818
Ordered Locus Names:Dole_2198
OrganismDesulfococcus oleovorans (strain DSM 6200 / Hxd3) [Complete proteome] [HAMAP]
Taxonomic identifier96561 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfobacterales › Desulfobacteraceae › Desulfococcus

Protein attributes

Sequence length134 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00818

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00818

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00818

Subcellular location

Cytoplasm By similarity HAMAP MF_00818.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
A8ZUH0 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 8EC5F7AC0C891925

FASTA13415,068
        10         20         30         40         50         60 
MSDNPQPPLP YTALSADTVG TKMLTVIEYA YRETRPIDVV IRQPEFTSLC PMTGLPDYGC 

        70         80         90        100        110        120 
ITIRYRPRHH IVELKSLKYY LLQYRNVGIF YEHVINRILN DLSGAVAPVW MEVSGEFTAR 

       130 
GGITTTVTAA TGDQ

« Hide

References

[1]"Complete sequence of Desulfococcus oleovorans Hxd3."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Wawrik B., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 6200 / Hxd3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000859 Genomic DNA. Translation: ABW68002.1.
RefSeqYP_001530079.1. NC_009943.1.

3D structure databases

ProteinModelPortalA8ZUH0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8ZUH0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5695044.
GenomeReviewsGene locus Dole_2198 in contig CP000859_GR.
KEGGdol:Dole_2198.
PATRIC21694523. VBIDesOle35880_2261.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG294103.
OMAFRNAGIF.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK09457.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8ZUH0_DESOH
AccessionPrimary (citable) accession number: A8ZUH0
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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