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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit A

Gene

gatA

Organism
Desulfococcus oleovorans (strain DSM 6200 / Hxd3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei78Charge relay systemUniRule annotation1
Active sitei153Charge relay systemUniRule annotation1
Active sitei177Acyl-ester intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciDOLE96561:G1GAC-153-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotation (EC:6.3.5.7UniRule annotation)
Short name:
Glu-ADT subunit AUniRule annotation
Gene namesi
Name:gatAUniRule annotation
Ordered Locus Names:Dole_0151
OrganismiDesulfococcus oleovorans (strain DSM 6200 / Hxd3)
Taxonomic identifieri96561 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobacteraceaeDesulfococcus
Proteomesi
  • UP000008561 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000951321 – 486Glutamyl-tRNA(Gln) amidotransferase subunit AAdd BLAST486

Proteomic databases

PRIDEiA8ZSP8

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Protein-protein interaction databases

STRINGi96561.Dole_0151

Structurei

3D structure databases

ProteinModelPortaliA8ZSP8
SMRiA8ZSP8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amidase family. GatA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3P Bacteria
COG0154 LUCA
HOGENOMiHOG000116699
KOiK02433
OMAiPITQNVE
OrthoDBiPOG091H00O9

Family and domain databases

Gene3Di3.90.1300.10, 1 hit
HAMAPiMF_00120 GatA, 1 hit
InterProiView protein in InterPro
IPR000120 Amidase
IPR020556 Amidase_CS
IPR023631 Amidase_dom
IPR036928 AS_sf
IPR004412 GatA
PANTHERiPTHR11895 PTHR11895, 1 hit
PfamiView protein in Pfam
PF01425 Amidase, 1 hit
SUPFAMiSSF75304 SSF75304, 1 hit
TIGRFAMsiTIGR00132 gatA, 1 hit
PROSITEiView protein in PROSITE
PS00571 AMIDASES, 1 hit

Sequencei

Sequence statusi: Complete.

A8ZSP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPYALTIHE ARQLLDKKEI SSVELTRSVF DRIERVEPKV GAYITLARES
60 70 80 90 100
ALSAAAAADT RLQSGGIAPL TGIPLAVKDL ICTTGLRTTC ASRMLETFMP
110 120 130 140 150
PYDATVIEKL KTQGAVITGK VNMDEFAMGS STEHSALGST KNPWNLACIP
160 170 180 190 200
GGSSGGSAAS VAADMCLGSL GSDTGGSIRQ PASHCGVVGI KPTYGRVSRY
210 220 230 240 250
GLVAFASSLD QIGVLAKDVT DSALLLSAIS GHDPSDSTSV PREVPDYAAS
260 270 280 290 300
CEKGLSGLTI GVCREYINAE GLDPEVADTV NRSIEHMKAQ GAACVEVSLP
310 320 330 340 350
HAQYAVAAYY VIAPAEASSN LARYDGVKYG FRDPEADSLL EMYARTRSRG
360 370 380 390 400
FGKEVQRRII IGTYCLSSGY YDAYYRKASQ VRSLIADDFK KAFETCDVIV
410 420 430 440 450
SPVAPTPAFE LGAKTEDPLT MYLSDIFTLS ANLAGVPGMS VPGGFSSTGL
460 470 480
PIGVQLIAGH FNEPALVRCA WNLEQAVNIA NKKPAL
Length:486
Mass (Da):51,404
Last modified:January 15, 2008 - v1
Checksum:i8D294D053CB8598E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000859 Genomic DNA Translation: ABW65961.1
RefSeqiWP_012173580.1, NC_009943.1

Genome annotation databases

EnsemblBacteriaiABW65961; ABW65961; Dole_0151
KEGGidol:Dole_0151

Similar proteinsi

Entry informationi

Entry nameiGATA_DESOH
AccessioniPrimary (citable) accession number: A8ZSP8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 15, 2008
Last modified: May 23, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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