Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A8Z660

- PNP_SULMW

UniProt

A8Z660 - PNP_SULMW

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Sulcia muelleri (strain GWSS)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi509 – 5091MagnesiumUniRule annotation
Metal bindingi515 – 5151MagnesiumUniRule annotation

GO - Molecular functioni

  1. 3'-5'-exoribonuclease activity Source: InterPro
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
  4. RNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. mRNA catabolic process Source: UniProtKB-HAMAP
  2. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding

Enzyme and pathway databases

BioCyciCSUL444179:GHLI-212-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:SMGWSS_214
OrganismiSulcia muelleri (strain GWSS)
Taxonomic identifieri444179 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesCandidatus Sulcia
ProteomesiUP000000781: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 728728Polyribonucleotide nucleotidyltransferasePRO_0000329890Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi444179.SMGWSS_214.

Structurei

3D structure databases

ProteinModelPortaliA8Z660.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini576 – 63863KHUniRule annotationAdd
BLAST
Domaini648 – 71568S1 motifUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
Contains 1 KH domain.UniRule annotation
Contains 1 S1 motif domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1185.
HOGENOMiHOG000218327.
KOiK00962.
OMAiPRWDWVA.
OrthoDBiEOG6WT8CC.

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view]
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiPF13014. KH_3. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view]
SMARTiSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8Z660-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIPELIKENL FLEDGRALSI ETGELARKAN GSAVVRMGNT SLLATVVISK
60 70 80 90 100
ESKEDFKFIP LTIDYREKYS AGGKIPGGYI KREGRPYDEE ILTMRLVDRL
110 120 130 140 150
LRPLFKDNYY NEIQIMISLL SYDINVLPDG LAGLVASTAV SISEISFQGP
160 170 180 190 200
VSTVRIIRIN DAFIINPGIE EIKKSDFYLD LDLDLDLIVG GTNNYIILVE
210 220 230 240 250
GEMREISEIE MMEAIVKAHK YIQLQIEAQI SLITKNKKFI KKKLYKIELY
260 270 280 290 300
NYYYKYINFN LNVFYIKEKI KFISYEEIDY IYKSCLFKQK RSNKIYNILK
310 320 330 340 350
KIKFHFYNES IVINNLEIDI IFDEIKKEII KNILFKENIR LDGRSLDDIR
360 370 380 390 400
NICSQVDCLP GVHGSAIFTR GETQALSTVT LGSSLDVNKI DNAIMRAKQR
410 420 430 440 450
FYLHYNFPPF STGEIKLLKG VSRREIGHGN LAQRALKNII PTTYTIRVVS
460 470 480 490 500
DVLESNGSSS MATVCASTLA LMDSGIIVKR PVSGISMGLI MNYLTGEAII
510 520 530 540 550
LSDLLGDEDY IGDMDFKITG TEYGMTACQM DIKISGITYD VLSYTIFKAK
560 570 580 590 600
KGLLFIIKKM LTTLSCPRKS LNITATKIYT FYIPKKLIGA VIGSGGKRIQ
610 620 630 640 650
EIQVSTETNI KIKEKNYLGV IEILGKNETK LKIAILKIKN ITFVPKVGTI
660 670 680 690 700
YKAKVKNIKK FGVFVKISKY LEGLLHIYEI SWLTKVESFI RKGDIISVKY
710 720
LGKNNKFRKI KLSHKMIFSR YYLNKNLK
Length:728
Mass (Da):82,950
Last modified:January 15, 2008 - v1
Checksum:i54CECA1F1A5C4BB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000770 Genomic DNA. Translation: ABS30611.1.
RefSeqiWP_012220914.1. NC_010118.1.
YP_001598007.1. NC_010118.1.

Genome annotation databases

EnsemblBacteriaiABS30611; ABS30611; SMGWSS_214.
GeneIDi5797221.
KEGGismg:SMGWSS_214.
PATRICi32019125. VBICanSul12747_0177.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000770 Genomic DNA. Translation: ABS30611.1 .
RefSeqi WP_012220914.1. NC_010118.1.
YP_001598007.1. NC_010118.1.

3D structure databases

ProteinModelPortali A8Z660.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 444179.SMGWSS_214.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS30611 ; ABS30611 ; SMGWSS_214 .
GeneIDi 5797221.
KEGGi smg:SMGWSS_214.
PATRICi 32019125. VBICanSul12747_0177.

Phylogenomic databases

eggNOGi COG1185.
HOGENOMi HOG000218327.
KOi K00962.
OMAi PRWDWVA.
OrthoDBi EOG6WT8CC.

Enzyme and pathway databases

BioCyci CSUL444179:GHLI-212-MONOMER.

Family and domain databases

Gene3Di 1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPi MF_01595. PNPase.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view ]
PANTHERi PTHR11252. PTHR11252. 1 hit.
Pfami PF13014. KH_3. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view ]
SMARTi SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
PROSITEi PS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Parallel genomic evolution and metabolic interdependence in an ancient symbiosis."
    McCutcheon J.P., Moran N.A.
    Proc. Natl. Acad. Sci. U.S.A. 104:19392-19397(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GWSS.

Entry informationi

Entry nameiPNP_SULMW
AccessioniPrimary (citable) accession number: A8Z660
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: January 15, 2008
Last modified: November 26, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3