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A8Z600 (A8Z600_SULMW) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Homoserine kinase EMBL ABS30551.1
Gene names
Name:thrB EMBL ABS30551.1
Ordered Locus Names:SMGWSS_140
OrganismSulcia muelleri (strain GWSS) [Complete proteome] [HAMAP]
Taxonomic identifier444179 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Candidatus Sulcia

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-homoserine = ADP + O-phospho-L-homoserine. SAAS SAAS000870

Pathway

Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. SAAS SAAS000870

Subcellular location

Cytoplasm By similarity SAAS SAAS000870.

Sequence similarities

Belongs to the GHMP kinase family. RuleBase RU004209

Sequences

Sequence LengthMass (Da)Tools
A8Z600 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: B09E936626143D02

FASTA31033,553
        10         20         30         40         50         60 
MKIIKVIAPA TIANIVCGFD VLGLAVNIPN DEIIIKITDI PGIRIKKIFG ANLSKNRKKN 

        70         80         90        100        110        120 
VISIALQALL NNINKSNIGF DIEISKNIQP GSGIGSSAAS AAGIVVGANY LLGNPFKKKD 

       130        140        150        160        170        180 
LIKFAMEGER LAGGVPHADN VAPAIIGGIT LIRSYKPLDI ISLRSPDNIW VSILHPEIEI 

       190        200        210        220        230        240 
KTSDAREILK HKILITEAIK QWGNLGALIA GLYKEDYDMI SRSLDDVIIE PIRAILIPAF 

       250        260        270        280        290        300 
NELKIKCKSI GALGGGISGS GPSVFMLSNG KKKAELVTNV MEHIYSKLEL NYKIYTSSIN 

       310 
RTGIVYYELI

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References

[1]"Parallel genomic evolution and metabolic interdependence in an ancient symbiosis."
McCutcheon J.P., Moran N.A.
Proc. Natl. Acad. Sci. U.S.A. 104:19392-19397(2007) [PubMed: 18048332] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000770 Genomic DNA. Translation: ABS30551.1.
RefSeqYP_001597947.1. NC_010118.1.

3D structure databases

ProteinModelPortalA8Z600.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8Z600.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5797158.
GenomeReviewsGene locus SMGWSS_140 in contig CP000770_GR.
KEGGsmg:SMGWSS_140.
PATRIC32018979. VBICanSul12747_0116.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646290.
OMAGSAHADN.
ProtClustDBPRK01212.

Family and domain databases

InterProIPR006204. GHMP_kinase.
IPR013750. GHMP_kinase_C.
IPR000870. Homoserine_kinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
Gene3DG3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK00872.
PfamPF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF000676. Homoser_kin. 1 hit.
PRINTSPR00958. HOMSERKINASE.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00191. ThrB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8Z600_SULMW
AccessionPrimary (citable) accession number: A8Z600
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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