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A8Z4X3 (A8Z4X3_STAAT) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase 2 HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr2 HAMAP MF_01201 EMBL ABX30062.1
Ordered Locus Names:USA300HOU_2065
OrganismStaphylococcus aureus (strain USA300 / TCH1516) [Complete proteome] [HAMAP] EMBL ABX30062.1
Taxonomic identifier451516 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 RuleBase RU004247 SAAS SAAS009006

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site391Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2651Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue391N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
A8Z4X3 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 52B3C88E9811956D

FASTA38242,823
        10         20         30         40         50         60 
MSDKYYRSAY MNVDLNAVAS NFKVFSTLHP NKTVMAVVKA NAYGLGSVKV ARHLMENGAT 

        70         80         90        100        110        120 
FFAVATLDEA IELRMHGITA KILVLGVLPA KDIDKAIQHR VALTVPSKQW LKEAIKNISG 

       130        140        150        160        170        180 
EQEKKLWLHI KLDTGMGRLG IKDTKTYQEV IEIIQQYEQL VFEGVFTHFA CADEPGDMTT 

       190        200        210        220        230        240 
EQYQRFKDMV NEAIKPEYIH CQNSAGSLLM DCQFCNAIRP GISLYGYYPS EYVQQKVKVH 

       250        260        270        280        290        300 
LKPSVQLIAN VVQTKTLQAG ESVSYGATYT ATDPTTIALL PIGYADGYLR IMQGSFVNVN 

       310        320        330        340        350        360 
GHQCEVIGRV CMDQTIVKVP DQVKAGDSVI LIDNHRESPQ SVEVVAEKQH TINYEVLCNL 

       370        380 
SRRLPRIYHD GDQRFVTNEL LK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000730 Genomic DNA. Translation: ABX30062.1.
RefSeqYP_001575941.1. NC_010079.1.

3D structure databases

ProteinModelPortalA8Z4X3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8Z4X3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000034211; EBSTAP00000033000; EBSTAG00000034209.
GeneID5775913.
GenomeReviewsGene locus USA300HOU_2065 in contig CP000730_GR.
KEGGsax:USA300HOU_2065.
PATRIC19599354. VBIStaAur36919_2155.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000023673.
HOGENOMHBG712172.
OMANWQIKAL.
ProtClustDBCLSK885747.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8Z4X3_STAAT
AccessionPrimary (citable) accession number: A8Z4X3
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info