A8Z3G0 (A8Z3G0_STAAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
(R)-2-hydroxyacid dehydrogenase EMBL ABX30540.1
EC=1.1.1.272 EMBL ABX30540.1

Gene names

Ordered Locus Names:

USA300HOU_2554

Organism

Staphylococcus aureus (strain USA300 / TCH1516) [Complete proteome] [HAMAP] EMBL ABX30540.1

Taxonomic identifier

451516 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. RuleBase RU003719

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003720 EMBL ABX30540.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	(R)-2-hydroxyacid dehydrogenase activity Inferred from electronic annotation. Source: EC NAD binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8Z3G0 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 08AFC19791ED4F8B	FASTA	342	38,338
	10 20 30 40 50 60 MNNKVKGDVK MTKIKIMSVR DEDMPYIKAW AEKHHVEVDI TKEALTDDNV EGVAGYDGLS 70 80 90 100 110 120 LSQQIPLSEH VYKRLNELGI KQIAQRSAGF DTYDLELANK YNFIVSNVPS YSPNSIAEFA 130 140 150 160 170 180 VNQAINVVRH FNQIQTKVRE HDFRWEPTIL SKSIKDLKVA VIGTGRIGRV VADIFANGYQ 190 200 210 220 230 240 SDVVAYDPFP NAKIATYVDY KDTIEEAVEG ADIVTLHVPA TKYNHYLFNA ELFKHFKKGA 250 260 270 280 290 300 VFVNCARGSL VDTKALLDAL DNGVIKGAAL DTYEFERKLF PSDQRGKTLN DPLLESLIDR 310 320 330 340 EDVILTPHIA FYTEAAVKNL IVDALDATLD VLQTGDTRLR VN

References

[1]

"Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus." Highlander S.K., Hulten K.G., Qin X., Jiang H., Yerrapragada S., Mason E.O. Jr., Shang Y., Williams T.M., Fortunov R.M., Liu Y., Igboeli O., Petrosino J., Tirumalai M., Uzman A., Fox G.E., Cardenas A.M., Muzny D.M., Hemphill L. , Ding Y., Dugan S., Blyth P.R., Buhay C.J., Dinh H.H., Hawes A.C., Holder M., Kovar C.L., Lee S.L., Liu W., Nazareth L.V., Wang Q., Zhou J., Kaplan S.L., Weinstock G.M. BMC Microbiol. 7:99-99(2007) [PubMed: 17986343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000730 Genomic DNA. Translation: ABX30540.1.
RefSeq	YP_001576419.1. NC_010079.1.
3D structure databases
ProteinModelPortal	A8Z3G0.
ModBase	Search...
Protein-protein interaction databases
STRING	A8Z3G0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000033626; EBSTAP00000032415; EBSTAG00000033624.
GeneID	5777452.
GenomeReviews	Gene locus USA300HOU_2554 in contig CP000730_GR.
KEGG	sax:USA300HOU_2554.
PATRIC	19600396. VBIStaAur36919_2666.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000024534.
HOGENOM	HBG731446.
OMA	EMVHQSF.
ProtClustDB	PRK08605.
Family and domain databases
InterPro	IPR006139. D-isomer_2_OHA_DH_cat_dom. IPR006140. D-isomer_2_OHA_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 2 hits.
KO	K03778.
Pfam	PF00389. 2-Hacid_dh. 1 hit. PF02826. 2-Hacid_dh_C. 1 hit. [Graphical view]
PROSITE	PS00065. D_2_HYDROXYACID_DH_1. 1 hit. PS00670. D_2_HYDROXYACID_DH_2. 1 hit. PS00671. D_2_HYDROXYACID_DH_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8Z3G0_STAAT

Accession

Primary (citable) accession number: A8Z3G0

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)