A8Z313 (A8Z313_STAAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hyaluronate lyase EMBL ABX30190.1
EC=4.2.2.1 EMBL ABX30190.1

Gene names

Name:	hysA EMBL ABX30190.1
Ordered Locus Names:	USA300HOU_2197

Organism

Staphylococcus aureus (strain USA300 / TCH1516) [Complete proteome] [HAMAP] EMBL ABX30190.1

Taxonomic identifier

451516 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	809 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL ABX30190.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro hyaluronate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8Z313 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 1D24F10471059EE4	FASTA	809	92,203
	10 20 30 40 50 60 MSMTYRIKKW QKLSTITLLM AGVITLNGGE FRSVDKHQIA VADTNVQTPD YEKLRNTWLD 70 80 90 100 110 120 VNYGYDKYDE NNPDMKKKFD ATEKEATNLL KEMKTESGRK YLWSGAETLE TNSSHMTRTY 130 140 150 160 170 180 RNIEKIAEAM RNPKTTLNTD ENKKKVKDAL EWLHKNAYGK EPDKKVKELS ENFTKTTGKN 190 200 210 220 230 240 TNLNWWDYEI GTPKSLTNTL ILLNDQFSNE EKKKFTAPIK TFAPDSDKIL SSVGKAELAK 250 260 270 280 290 300 GGNLVDISKV KLLECIIEED KDMMKKSIDS FNKVFTYVQD SATGKERNGF YKDGSYIDHQ 310 320 330 340 350 360 DVPYTGAYGV VLLEGISQMM PMIKETPFND KTQNDTTLKS WIDDGFMPLI YKGEMMDLSR 370 380 390 400 410 420 GRAISRENET SHSASATVMK SLLRLSDAMD DSTKAKYKKI VKSSVESDSS YKQNDYLNSY 430 440 450 460 470 480 SDIDKMKSLM TDNSISKNGL TQQLKIYNDM DRVTYHNKDL DFAFGLSMTS KNVARYESIN 490 500 510 520 530 540 GENLKGWHTG AGMSYLYNSD VKHYHDNFWV TADMKRLSGT TTLDNEILKD TDDKKSSKTF 550 560 570 580 590 600 VGGTKVDDQH ASIGMDFENQ DKTLTAKKSY FILNDKIVFL GTGIKSTDSS KNPVTTIENR 610 620 630 640 650 660 KANGYTLYTD DKQTTNSDNQ ENNSVFLEST DTKKNIGYHF LNKPKITVKK ESHTGKWKEI 670 680 690 700 710 720 NKSQKDTQKT DEYYEVTQKH SNSDNKYGYV LYPGLSKDVF KTKKDEVTVV KQEDDFHVVK 730 740 750 760 770 780 DNESVWAGVN YSNSTQTFDI NNTKVEVKAK GMFILKKKDD NTYECSFYNP ESTNSASDIE 790 800 SKISMTGYSI TNKNTSTSNE SGVHFELTK

References

[1]

"Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus." Highlander S.K., Hulten K.G., Qin X., Jiang H., Yerrapragada S., Mason E.O. Jr., Shang Y., Williams T.M., Fortunov R.M., Liu Y., Igboeli O., Petrosino J., Tirumalai M., Uzman A., Fox G.E., Cardenas A.M., Muzny D.M., Hemphill L. , Ding Y., Dugan S., Blyth P.R., Buhay C.J., Dinh H.H., Hawes A.C., Holder M., Kovar C.L., Lee S.L., Liu W., Nazareth L.V., Wang Q., Zhou J., Kaplan S.L., Weinstock G.M. BMC Microbiol. 7:99-99(2007) [PubMed: 17986343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000730 Genomic DNA. Translation: ABX30190.1.
RefSeq	YP_001576069.1. NC_010079.1.
3D structure databases
ProteinModelPortal	A8Z313.
ModBase	Search...
Protein-protein interaction databases
STRING	A8Z313.
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000035934; EBSTAP00000034723; EBSTAG00000035932.
GeneID	5775495.
GenomeReviews	Gene locus USA300HOU_2197 in contig CP000730_GR.
KEGG	sax:USA300HOU_2197.
PATRIC	19599641. VBIStaAur36919_2289.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000023753.
HOGENOM	HBG693731.
OMA	GSYIDHT.
ProtClustDB	CLSK885824.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR011071. Lyase_8-like_C. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
KO	K01727.
Pfam	PF02278. Lyase_8. 1 hit. PF02884. Lyase_8_C. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF74650. Gal_mut_like. 1 hit. SSF49863. Lyase_like_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8Z313_STAAT

Accession

Primary (citable) accession number: A8Z313

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)