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A8Z0A2 (A8Z0A2_STAAT) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Regulatory protein spx HAMAP-Rule MF_01132
Gene names
Name:spxA HAMAP-Rule MF_01132
Ordered Locus Names:USA300HOU_0955 EMBL ABX28976.1
OrganismStaphylococcus aureus (strain USA300 / TCH1516) [Complete proteome] [HAMAP] EMBL ABX28976.1
Taxonomic identifier451516 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length131 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress By similarity. HAMAP-Rule MF_01132

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01132.

Sequence similarities

Belongs to the ArsC family. Spx subfamily. HAMAP-Rule MF_01132

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Disulfide bond10 ↔ 13Redox-active By similarity HAMAP-Rule MF_01132

Sequences

Sequence LengthMass (Da)Tools
A8Z0A2 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 89F67A54666699BF

FASTA13115,441
        10         20         30         40         50         60 
MVTLFTSPSC TSCRKAKAWL QEHDIPYTER NIFSEHLTID EIKQILKMTE DGTDEIISTR 

        70         80         90        100        110        120 
SKTYQKLNVD IDSLPLQDLY SIIQDNPGLL RRPIILDNKR LQVGYNEDEI RRFLPRKVRT 

       130 
FQLQEAQRMV D

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000730 Genomic DNA. Translation: ABX28976.1.
RefSeqYP_001574855.1. NC_010079.1.

3D structure databases

ProteinModelPortalA8Z0A2.
SMRA8Z0A2. Positions 1-118.
ModBaseSearch...

Protein-protein interaction databases

STRING451516.USA300HOU_0955.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX28976; ABX28976; USA300HOU_0955.
GeneID5777570.
KEGGsax:USA300HOU_0955.
PATRIC19596948. VBIStaAur36919_0996.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1393.
HOGENOMHOG000059715.
KOK16509.
OMARPIIMDD.
ProtClustDBPRK01655.

Enzyme and pathway databases

BioCycSAUR451516:GJQ4-974-MONOMER.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
HAMAPMF_01132. SpxA.
InterProIPR006660. Arsenate_reductase-like.
IPR012336. Thioredoxin-like_fold.
IPR023731. Tscrpt_reg_Spx.
IPR006504. Tscrpt_reg_Spx/MgsR.
[Graphical view]
PfamPF03960. ArsC. 1 hit.
[Graphical view]
SUPFAMSSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMsTIGR01617. arsC_related. 1 hit.
PROSITEPS51353. ARSC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8Z0A2_STAAT
AccessionPrimary (citable) accession number: A8Z0A2
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: May 1, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info