Skip Header

Contribute Send feedback
Read comments (?) or add your own

A8Z003 (A8Z003_STAAT) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase RuleBase RU003410
EC=1.17.4.1 RuleBase RU003410
Gene names
Name:nrdE EMBL ABX28776.1
Ordered Locus Names:USA300HOU_0755 EMBL ABX28776.1
OrganismStaphylococcus aureus (strain USA300 / TCH1516) [Complete proteome] [HAMAP] EMBL ABX28776.1
Taxonomic identifier451516 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length701 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. RuleBase RU003410

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. RuleBase RU003410

Pathway

Genetic information processing; DNA replication. RuleBase RU003410

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase large chain family. RuleBase RU003410

Sequences

Sequence LengthMass (Da)Tools
A8Z003 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: A8B49FE4A1B652B3

FASTA70180,126
        10         20         30         40         50         60 
MKTMEEKKYN HIELNNEVTK RREDGFFSLE KDQEALVAYL EEVKDKTIFF DTEIERLRYL 

        70         80         90        100        110        120 
VDNDFYFNVF DIYSEADLIE ITDYAKSIPF NFASYMSASK FFKDYALKTN DKSQYLEDYN 

       130        140        150        160        170        180 
QHVAIVALYL ANGNKAQAKQ FISAMVEQRY QPATPTFLNA GRARRGELVS CFLLEVDDSL 

       190        200        210        220        230        240 
NSINFIDSTA KQLSKIGGGV AINLSKLRAR GEAIKGIKGV AKGVLPIAKS LEGGFSYADQ 

       250        260        270        280        290        300 
LGQRPGAGAV YLNIFHYDVE EFLDTKKVNA DEDLRLSTIS TGLIVPSKFF DLAKEGKDFY 

       310        320        330        340        350        360 
MFAPHTVKEE YGVTLDDIDL EKYYDDMVAN PNVEKKKKNA REMLNLIAQT QLQSGYPYLM 

       370        380        390        400        410        420 
FKDNANRVHP NSNIGQIKMS NLCTEIFQLQ ETSIINDYGI EDEIKRDISC NLGSLNIVNV 

       430        440        450        460        470        480 
MESGKFRDSV HSGMDALTVV SDVANIQNAP GVRKANSELH SVGLGVMNLH GYLAKNKIGY 

       490        500        510        520        530        540 
ESEEAKDFAN IFFMMMNFYS IERSMEIAKE RGIKYQDFEK SDYANGKYFE FYTTQEFEPQ 

       550        560        570        580        590        600 
FEKVRELFDG MAIPTSEDWK KLQQDVEQYG LYHAYRLAIA PTQSISYVQN ATSSVMPIVD 

       610        620        630        640        650        660 
QIERRTYGNA ETFYPMPFLS PQTMWYYKSA FNTDQMKLID LIATIQTHID QGISTILYVN 

       670        680        690        700 
SEISTRELAR LYVYAHYKGL KSLYYTRNKL LSVEECTSCS I

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000730 Genomic DNA. Translation: ABX28776.1.
RefSeqYP_001574655.1. NC_010079.1.

3D structure databases

ProteinModelPortalA8Z003.
ModBaseSearch...

Protein-protein interaction databases

STRING451516.USA300HOU_0755.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX28776; ABX28776; USA300HOU_0755.
GeneID5777518.
KEGGsax:USA300HOU_0755.
PATRIC19596556. VBIStaAur36919_0797.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0209.
HOGENOMHOG000246165.
KOK00525.
OMAQHVDQGM.
ProtClustDBPRK07632.

Enzyme and pathway databases

BioCycSAUR451516:GJQ4-772-MONOMER.
UniPathwayUPA00326.

Family and domain databases

InterProIPR013346. NrdE_NrdA.
IPR026459. RNR_1b_NrdE.
IPR000788. RNR_lg_C.
IPR013509. RNR_lsu_N.
IPR013554. RNR_N.
IPR008926. RNR_R1-su_N.
[Graphical view]
PfamPF02867. Ribonuc_red_lgC. 1 hit.
PF00317. Ribonuc_red_lgN. 1 hit.
PF08343. RNR_N. 1 hit.
[Graphical view]
PRINTSPR01183. RIBORDTASEM1.
SUPFAMSSF48168. Ribonucleo_red_N. 1 hit.
TIGRFAMsTIGR02506. NrdE_NrdA. 1 hit.
TIGR04170. RNR_1b_NrdE. 1 hit.
PROSITEPS00089. RIBORED_LARGE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8Z003_STAAT
AccessionPrimary (citable) accession number: A8Z003
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info