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A8YXM7 (IF1_LACH4) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-1
Gene names
Name:infA
Ordered Locus Names:lhv_0334
OrganismLactobacillus helveticus (strain DPC 4571) [Complete proteome] [HAMAP]
Taxonomic identifier405566 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length73 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 By similarity. HAMAP-Rule MF_00075

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00075.

Sequence similarities

Belongs to the IF-1 family.

Contains 1 S1-like domain.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionInitiation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7373Translation initiation factor IF-1 HAMAP-Rule MF_00075
PRO_0000338847

Regions

Domain1 – 7272S1-like

Sequences

Sequence LengthMass (Da)Tools
A8YXM7 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: A1A02563EB0CFC62

FASTA738,274
        10         20         30         40         50         60 
MAKDDVIEVE GKVVDTLPNA MFKVELENGA TILAHVSGKI RMHYIRILPG DRVTVELSPY 

        70 
DLTKGRITYR FIK 

« Hide

References

[1]"Genome sequence of Lactobacillus helveticus: an organism distinguished by selective gene loss and IS element expansion."
Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K., McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F., Beresford T., Ross R.P.
J. Bacteriol. 190:727-735(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DPC 4571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000517 Genomic DNA. Translation: ABX26558.1.
RefSeqYP_001576849.1. NC_010080.1.

3D structure databases

ProteinModelPortalA8YXM7.
SMRA8YXM7. Positions 2-70.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING405566.lhv_0334.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX26558; ABX26558; lhv_0334.
GeneID5772472.
KEGGlhe:lhv_0334.
PATRIC22232686. VBILacHel91643_0346.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0361.
HOGENOMHOG000221323.
KOK02518.
OMAGGQFRRR.
OrthoDBEOG6384SC.
ProtClustDBPRK00276.

Enzyme and pathway databases

BioCycLHEL405566:GJEN-299-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00075. IF_1.
InterProIPR012340. NA-bd_OB-fold.
IPR022967. RNA-binding_domain_S1.
IPR006196. RNA-binding_domain_S1_IF1.
IPR004368. TIF_IF1.
[Graphical view]
PfamPF01176. eIF-1a. 1 hit.
[Graphical view]
SMARTSM00316. S1. 1 hit.
[Graphical view]
SUPFAMSSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00008. infA. 1 hit.
PROSITEPS50832. S1_IF1_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF1_LACH4
AccessionPrimary (citable) accession number: A8YXM7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: January 15, 2008
Last modified: February 19, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries