A8YW25 (A8YW25_LACH4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Galactose-1-phosphate uridylyltransferase HAMAP MF_00571
Short name=Gal-1-P uridylyltransferase HAMAP MF_00571
EC=2.7.7.12 HAMAP MF_00571

Alternative name(s):
UDP-glucose--hexose-1-phosphate uridylyltransferase HAMAP MF_00571

Gene names

Name:	galT HAMAP MF_00571
Ordered Locus Names:	lhv_1500

Organism

Lactobacillus helveticus (strain DPC 4571) [Complete proteome] [HAMAP]

Taxonomic identifier

405566 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	487 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm By similarity HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family. HAMAP MF_00571

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism HAMAP MF_00571
Cellular component	Cytoplasm HAMAP MF_00571
Molecular function	Nucleotidyltransferase HAMAP MF_00571 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8YW25 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 4CEEAAFD18E7E190	FASTA	487	55,478
	10 20 30 40 50 60 MKIIEKFADE VINSGAYEPL DRVYVINKIR ALVGDHDEEE NDQPAAKQLV DLAVKNEKIP 70 80 90 100 110 120 DDITSREVLN DQLYDLATPT PSKTNSIFWQ KMQKSSEENT DWFYKLCEDN NYVKKEAIAK 130 140 150 160 170 180 NVVFSGTSSK GHSLEITINL SKPEKDPKAI AAAAHATGKK YPQCALCLEN EGYLGGYGKN 190 200 210 220 230 240 ARSNLRIIRM NIAGRPWGFQ YSPYAYFNEH CIFLDQKHIP MVINQQTLIN LVEIEKIFPH 250 260 270 280 290 300 YFVGSNADLP IVGGSMLAHE HYQGGRHTFP MMKAGIKKNI MFDSYPKVVA GIVDWPMSDL 310 320 330 340 350 360 RLTSDNSLDL IDLGSKIIKF WDNYSDTARD IKAYEGETRH HTVTPIMHRE GKNFVLDLVL 370 380 390 400 410 420 RDNNTSEKYP LGIFHPHKQL WHIKKENIGL IEVMGRAILP GRLKSELEEV KKYWLGEDNK 430 440 450 460 470 480 MAASHKEWAD QVKAENEISL DNVDQVMEQS LVEVFEQVLQ DAGVFKNNAD GEEGWDKFIT ALTKEIK

References

[1]

"Genome sequence of Lactobacillus helveticus: an organism distinguished by selective gene loss and IS element expansion." Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K., McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F., Beresford T., Ross R.P. J. Bacteriol. 190:727-735(2008) [PubMed: 17993529] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000517 Genomic DNA. Translation: ABX27452.1.
RefSeq	YP_001577753.1. NC_010080.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A8YW25.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5771418.
GenomeReviews	Gene locus lhv_1500 in contig CP000517_GR.
KEGG	lhe:lhv_1500.
PATRIC	22235259. VBILacHel91643_1579.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG337915.
OMA	HYFIGSN.
ProtClustDB	PRK05270.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR023425. GalP_uridyl_Trfase_II_CS. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
KO	K00965.
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8YW25_LACH4

Accession

Primary (citable) accession number: A8YW25

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)