A8YVP6 (A8YVP6_LACH4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Ordered Locus Names:

lhv_1327

Organism

Lactobacillus helveticus (strain DPC 4571) [Complete proteome] [HAMAP]

Taxonomic identifier

405566 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Transferase RuleBase RU003985
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8YVP6 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 89C9D4E09C9CB053	FASTA	309	32,612
	10 20 30 40 50 60 MSTIYNSVTE LIGNTPLLKL NRVVPNDAAD VYVKLEFENP AGSIKDRIAL AMIEKAEREG 70 80 90 100 110 120 NLKPGGTIVE PTSGNTGIGL AMVAAAKDYH IIIVMPETMS VERRKLMKGY GAELILTPGA 130 140 150 160 170 180 DGMKGSIAKA EKLVKEKGYF MPMQFENTEN PNIHELTTGP EIIAAMNGIG KSVDAFVAGV 190 200 210 220 230 240 GTGGTLSGIG HALRRENPST KIFALEPTES PLLKDGKTGK HGIQGIAAGF IPKNLDKDIY 250 260 270 280 290 300 DDIITVSTDE AMATAREVAK NEGFLPGISA GANIHGAIEI AKKLGKGHAV VTVVPDGGDR YLSTALFNA

References

[1]

"Genome sequence of Lactobacillus helveticus: an organism distinguished by selective gene loss and IS element expansion." Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K., McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F., Beresford T., Ross R.P. J. Bacteriol. 190:727-735(2008) [PubMed: 17993529] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000517 Genomic DNA. Translation: ABX27333.1.
RefSeq	YP_001577624.1. NC_010080.1.
3D structure databases
ProteinModelPortal	A8YVP6.
SMR	A8YVP6. Positions 1-308.
ModBase	Search...
Protein-protein interaction databases
STRING	A8YVP6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5771570.
GenomeReviews	Gene locus lhv_1327 in contig CP000517_GR.
KEGG	lhe:lhv_1327.
PATRIC	22234906. VBILacHel91643_1404.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG748215.
OMA	SAGANIH.
ProtClustDB	CLSK936836.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR005856. Cys_synthKM. IPR005859. CysK. IPR001926. PyrdxlP-dep_enz_bsu. [Graphical view]
KO	K01738.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMs	TIGR01139. CysK. 1 hit. TIGR01136. CysKM. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8YVP6_LACH4

Accession

Primary (citable) accession number: A8YVP6

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)