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A8YUJ0 (A8YUJ0_LACH4) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length199 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020634

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020634.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124 RuleBase RU004165

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding93 – 964ATP By similarity HAMAP-Rule MF_00124

Sites

Active site941Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1511Zinc By similarity HAMAP-Rule MF_00124
Metal binding1541Zinc By similarity HAMAP-Rule MF_00124
Metal binding1881Zinc By similarity HAMAP-Rule MF_00124
Metal binding1911Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
A8YUJ0 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: CA17E88399FDD017

FASTA19922,518
        10         20         30         40         50         60 
MSQLFFRYGA MSSGKTIEIL KVAHNYEAQG RKIALMTSGL DNRSGVGTVA SRIGLHRKAI 

        70         80         90        100        110        120 
PITADMNLYT YIEKMNSHDL ADGKGKLACV LIDEAQFLKR HHVLECAKIV DEFNIPVMAF 

       130        140        150        160        170        180 
GLKNDFQNHL FEGSENLLIF ADKIEEMKTI CHYCGHKATM NLRVNNGKPV YEGEQVQIGG 

       190 
DESYYPVCRY HYFHPGIQR 

« Hide

References

[1]"Genome sequence of Lactobacillus helveticus, an organism distinguished by selective gene loss and insertion sequence element expansion."
Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K., McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F., Beresford T., Ross R.P.
J. Bacteriol. 190:727-735(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DPC 4571 EMBL ABX26928.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000517 Genomic DNA. Translation: ABX26928.1.
RefSeqYP_001577219.1. NC_010080.1.

3D structure databases

ProteinModelPortalA8YUJ0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING405566.lhv_0801.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX26928; ABX26928; lhv_0801.
GeneID5771999.
KEGGlhe:lhv_0801.
PATRIC22233758. VBILacHel91643_0833.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076391.
KOK00857.
OMAAIPITAD.
OrthoDBEOG69D3J2.

Enzyme and pathway databases

BioCycLHEL405566:GJEN-749-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8YUJ0_LACH4
AccessionPrimary (citable) accession number: A8YUJ0
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: July 9, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)