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A8YUI5

- G6PI_LACH4

UniProt

A8YUI5 - G6PI_LACH4

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, lhv_0795
Organism
Lactobacillus helveticus (strain DPC 4571)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei287 – 2871Proton donor By similarity
Active sitei308 – 3081 By similarity
Active sitei422 – 4221 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciLHEL405566:GJEN-741-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:lhv_0795
OrganismiLactobacillus helveticus (strain DPC 4571)
Taxonomic identifieri405566 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000000790: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 446446Glucose-6-phosphate isomeraseUniRule annotation
PRO_1000072396Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi405566.lhv_0795.

Structurei

3D structure databases

ProteinModelPortaliA8YUI5.
SMRiA8YUI5. Positions 4-445.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiQVIFIGN.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8YUI5-1 [UniParc]FASTAAdd to Basket

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MSLINFDSSK LTPFVHENEL GEMQAMVNAA NTELRNGTGA GSDFRGWLDL    50
PVDYDKDEFA RIKKAAKKIQ GDSEVLICIG IGGSYLGAQA AIELLNSNFY 100
GKEKTDMPIV VFCGNSLSGS YLYDLIEWLG DKDFSINVIS KSGTTTEPSV 150
AFRIFKDKLI KKYGKEEAAK RIYATTDRQK GALKTEADAE GYEEFVVPDD 200
IGGRYSVLTA VGLLPIAAAG ADIDALMKGA ADARADYTDT DVHKNSPYQY 250
AALRNILYRK GYTTEIVENY EPSLRMFGEW CKQLMGESEG KDNKGIWPSS 300
ANFTTDLHSL GQYIQEGLRN LFETVIRVEN PRHDVKIPGD EKNLDQLNFL 350
EGKSLNYVND RAYEGVVLAH TDGGVPVMTV NIPDQTEHTL GYMIYFFELA 400
IAISGYLNGI NPFNQPGVEE YKRNMFGLLN KPGYENLHDD LTKRLK 446
Length:446
Mass (Da):49,634
Last modified:January 15, 2008 - v1
Checksum:i681BDF98B51060BB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000517 Genomic DNA. Translation: ABX26923.1.
RefSeqiYP_001577214.1. NC_010080.1.

Genome annotation databases

EnsemblBacteriaiABX26923; ABX26923; lhv_0795.
GeneIDi5772006.
KEGGilhe:lhv_0795.
PATRICi22233740. VBILacHel91643_0826.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000517 Genomic DNA. Translation: ABX26923.1 .
RefSeqi YP_001577214.1. NC_010080.1.

3D structure databases

ProteinModelPortali A8YUI5.
SMRi A8YUI5. Positions 4-445.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 405566.lhv_0795.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABX26923 ; ABX26923 ; lhv_0795 .
GeneIDi 5772006.
KEGGi lhe:lhv_0795.
PATRICi 22233740. VBILacHel91643_0826.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi QVIFIGN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci LHEL405566:GJEN-741-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Lactobacillus helveticus: an organism distinguished by selective gene loss and IS element expansion."
    Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K., McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F., Beresford T., Ross R.P.
    J. Bacteriol. 190:727-735(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DPC 4571.

Entry informationi

Entry nameiG6PI_LACH4
AccessioniPrimary (citable) accession number: A8YUI5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 15, 2008
Last modified: June 11, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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