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A8YUI5

- G6PI_LACH4

UniProt

A8YUI5 - G6PI_LACH4

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Lactobacillus helveticus (strain DPC 4571)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (15 Jan 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei287 – 2871Proton donorUniRule annotation
    Active sitei308 – 3081UniRule annotation
    Active sitei422 – 4221UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciLHEL405566:GJEN-741-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:lhv_0795
    OrganismiLactobacillus helveticus (strain DPC 4571)
    Taxonomic identifieri405566 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
    ProteomesiUP000000790: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 446446Glucose-6-phosphate isomerasePRO_1000072396Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi405566.lhv_0795.

    Structurei

    3D structure databases

    ProteinModelPortaliA8YUI5.
    SMRiA8YUI5. Positions 4-445.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiQVIFIGN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8YUI5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLINFDSSK LTPFVHENEL GEMQAMVNAA NTELRNGTGA GSDFRGWLDL    50
    PVDYDKDEFA RIKKAAKKIQ GDSEVLICIG IGGSYLGAQA AIELLNSNFY 100
    GKEKTDMPIV VFCGNSLSGS YLYDLIEWLG DKDFSINVIS KSGTTTEPSV 150
    AFRIFKDKLI KKYGKEEAAK RIYATTDRQK GALKTEADAE GYEEFVVPDD 200
    IGGRYSVLTA VGLLPIAAAG ADIDALMKGA ADARADYTDT DVHKNSPYQY 250
    AALRNILYRK GYTTEIVENY EPSLRMFGEW CKQLMGESEG KDNKGIWPSS 300
    ANFTTDLHSL GQYIQEGLRN LFETVIRVEN PRHDVKIPGD EKNLDQLNFL 350
    EGKSLNYVND RAYEGVVLAH TDGGVPVMTV NIPDQTEHTL GYMIYFFELA 400
    IAISGYLNGI NPFNQPGVEE YKRNMFGLLN KPGYENLHDD LTKRLK 446
    Length:446
    Mass (Da):49,634
    Last modified:January 15, 2008 - v1
    Checksum:i681BDF98B51060BB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000517 Genomic DNA. Translation: ABX26923.1.
    RefSeqiYP_001577214.1. NC_010080.1.

    Genome annotation databases

    EnsemblBacteriaiABX26923; ABX26923; lhv_0795.
    GeneIDi5772006.
    KEGGilhe:lhv_0795.
    PATRICi22233740. VBILacHel91643_0826.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000517 Genomic DNA. Translation: ABX26923.1 .
    RefSeqi YP_001577214.1. NC_010080.1.

    3D structure databases

    ProteinModelPortali A8YUI5.
    SMRi A8YUI5. Positions 4-445.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 405566.lhv_0795.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABX26923 ; ABX26923 ; lhv_0795 .
    GeneIDi 5772006.
    KEGGi lhe:lhv_0795.
    PATRICi 22233740. VBILacHel91643_0826.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi QVIFIGN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci LHEL405566:GJEN-741-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Lactobacillus helveticus: an organism distinguished by selective gene loss and IS element expansion."
      Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K., McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F., Beresford T., Ross R.P.
      J. Bacteriol. 190:727-735(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DPC 4571.

    Entry informationi

    Entry nameiG6PI_LACH4
    AccessioniPrimary (citable) accession number: A8YUI5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3