A8YTC0 (A8YTC0_LACH4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2 HAMAP MF_01039
Short name=BPG-dependent PGAM 2 HAMAP MF_01039
Short name=PGAM 2 HAMAP MF_01039
Short name=Phosphoglyceromutase 2 HAMAP MF_01039
Short name=dPGM 2 HAMAP MF_01039
EC=5.4.2.1 HAMAP MF_01039

Gene names

Name:	gpmA2 HAMAP MF_01039
Ordered Locus Names:	lhv_0354

Organism

Lactobacillus helveticus (strain DPC 4571) [Complete proteome] [HAMAP]

Taxonomic identifier

405566 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	226 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01039 RuleBase RU004512
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039 RuleBase RU004512 SAAS SAAS005952
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039 RuleBase RU004512
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. HAMAP MF_01039

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_01039 SAAS SAAS005952
Molecular function	Isomerase HAMAP MF_01039 SAAS SAAS005952
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity HAMAP MF_01039
	Active site	178	1	By similarity HAMAP MF_01039
	Site	61	1	Interaction with carboxyl group of phosphoglycerates By similarity HAMAP MF_01039

Sequences

	Sequence		Length	Mass (Da)
	A8YTC0 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 003F1574AA3818E8	FASTA	226	25,738
	10 20 30 40 50 60 MAKLVLVRHG ESVANAANVY TGWNDVPLTK KGEQQAKKAG ELINTISDFA PTHIHTSVLS 70 80 90 100 110 120 RAIVTANIVA ETCNLLWLPM TKTWRLNERH YGALRGLNKD TSRKVFGVEQ VLLWRRSFDS 130 140 150 160 170 180 VPPKQGSPVI DRRYKLCDQH LMPRAESLHQ TQKRLMPYYY DHIASRLLNG EDQLIVAHGS 190 200 210 220 SLRALIKKLE NINNHDIVNL EVPNAEPIVY TMDEQLNIVK KEILRS

References

[1]

"Genome sequence of Lactobacillus helveticus: an organism distinguished by selective gene loss and IS element expansion." Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K., McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F., Beresford T., Ross R.P. J. Bacteriol. 190:727-735(2008) [PubMed: 17993529] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000517 Genomic DNA. Translation: ABX26576.1.
RefSeq	YP_001576867.1. NC_010080.1.
3D structure databases
ProteinModelPortal	A8YTC0.
ModBase	Search...
Protein-protein interaction databases
STRING	A8YTC0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5772450.
GenomeReviews	Gene locus lhv_0354 in contig CP000517_GR.
KEGG	lhe:lhv_0354.
PATRIC	22232730. VBILacHel91643_0368.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG658938.
OMA	ESTANRD.
ProtClustDB	CLSK2516631.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA. [Tree]
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
KO	K01834.
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. Pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8YTC0_LACH4

Accession

Primary (citable) accession number: A8YTC0

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)