Unreviewed, UniProtKB/TrEMBL A8YP94 (A8YP94_STIAU)

Names and origin

Protein names

Submitted name:
Polyketide synthase AufF EMBL CAO98849.1

Gene names

Name:

aufF EMBL CAO98849.1

Organism

Stigmatella aurantiaca EMBL CAO98849.1

Taxonomic identifier

41 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Cystobacteraceae › Stigmatella

Protein attributes

Sequence length	3360 AA.
Sequence status	Complete.
Protein existence	Predicted.

Ontologies

Keywords
Molecular function	Transferase RuleBase RU000693V1
Gene Ontology (GO)
Biological process	biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8YP94-1 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: F17DA07FC8F2DB71	FASTA	3,360	356,057
	10 20 30 40 50 60 MVALKRAKEQ LEANERQRTE PIAVVGLACR FPGGANDLEG YWRLLERGVD AVREIPPGRV 70 80 90 100 110 120 PADPAFPQTV SSAALLDDVE RFDAEFFGIS AREAERLDPQ QRLLLEVTWE ALEVAGHAPN 130 140 150 160 170 180 GLSGSRTGVY VGIGSPDYLR RILRCNPSDI DGQSFTGSLA SVAAGRLAYI LGLQGPCMAI 190 200 210 220 230 240 DTACSSSLVA LHQACMSLRN GESDLALAGG VNLILSPESS YVLGQLKALS PDGRCKTFDA 250 260 270 280 290 300 RANGYVRGEG CGMVVLKRLT DAQRDGDHIW ALVRGSAINQ DGRSAGLTAP NLLAQQALLR 310 320 330 340 350 360 QALRNARVEP EQIGYVETHG TGTPLGDPIE IEALTAVLGK PRADGSACVL GAVKTNIGHL 370 380 390 400 410 420 EAAAGVASLI KAILAFKHQA IPPNLHFRAL NPRITLTGTP FVMSDGRQPW RAGSKPRLAE 430 440 450 460 470 480 ISSFGISGTN AAVILEEPPA PAPATVSSDR THHVLTLSAR SPQALGHVVA NAAKHLRTAE 490 500 510 520 530 540 PASLRDFCFT SRSGRAHFAY RAAFAASSVE QLQGMLDEWV ANKESGTPEA SDAASRRPKI 550 560 570 580 590 600 AFLFTGQGSQ YAGMGRGLHR SEPVFRAALD RCAQLFKAEL PRPLLEVMWQ DNPAELDQTL 610 620 630 640 650 660 YSQPALFSLE YALVALWRSW GIEPDVVLGH SLGEYAAATA AGVISLEDAC RLVAARARAC 670 680 690 700 710 720 QALGPGGAMA AVEAEPALVE AVVAELGGGL AIAAYNGPKN LSLSGPAEQV RAASENLSRR 730 740 750 760 770 780 GAKIKPINTS CAFHSPLMAP MVAPFAEQVA RVSFSAPRVI WITNVTADRA ANDFDAADYW 790 800 810 820 830 840 SRQLCAPVRF AEGVQRAREL GCDVWVEIGP NPVLLGAVSR SLDEPQVTAP SLHHGRDDDA 850 860 870 880 890 900 VLARAVATLY AQGAKLDWQA FDASFARRRV PLPTYPFERE RYWFPLAPSP ALLPQASVGR 910 920 930 940 950 960 GHPLLGERLK LPGREIHFTN RLSAAHPEEL NEHRVYGQVV VPAALYVAAF LAAVRELSGG 970 980 990 1000 1010 1020 AAIEDVAFTR ALAIPEKSKA EGAPVAVVVT PGEPAARLSF FGEGTEPAAE WTLHASAMAS 1030 1040 1050 1060 1070 1080 LRPVNAATAK LHELRGRCQQ AAIPEKVLAS VWTDGGADHA PAPTMSLGPR FRRIAELWIG 1090 1100 1110 1120 1130 1140 SSEALARLTL NAPPEQAIRR SNPMDEHWQV PLTIIDSCFQ LLGIAAFASE AHEAWMPIGI 1150 1160 1170 1180 1190 1200 DRVELHPGAV PQGTEVWAHT AAALAGDGSL VRGDVRLLDP SGTVLVTLSG VSLKRVSQAA 1210 1220 1230 1240 1250 1260 LLQPPAWRQW MYELTWRRLE QTRSTAASAV ANRSFAVVLD RHGYGERFAR EVEARGGTVT 1270 1280 1290 1300 1310 1320 RFAGHQELEL GQPLDTTHVM AFLALDGGTP EEVTGRALAL LQVASRLPWR RAPRFWWLTS 1330 1340 1350 1360 1370 1380 GAQSVEGEQS PISIAQASLW GLARCAALEL PDLWGGLVDL DPRDGADGAA RLLEVLAGTD 1390 1400 1410 1420 1430 1440 DQLAVRSGAL FTARLETLRR RDVAPSPLRL RDDATYLISG GLGGTGWPLV ESWIERGARH 1450 1460 1470 1480 1490 1500 LVLLGRSAPS AEKQQQLADY AQRGITVRVL GVDITDGAAV AARWASVQAE LPPLRGVVHA 1510 1520 1530 1540 1550 1560 AGILDDAALL RHSARHLRDV LAPKLQGGEN LRRIAEGASL DFFVLFSSLA GVLGSPGQAS 1570 1580 1590 1600 1610 1620 YAAANAGLDA FAHELRSRGV PALSIAWGPW EVGFAAGHQE TLAARGVAPL PVNLAIEALG 1630 1640 1650 1660 1670 1680 ECIALGNTHL VVTAADLRAV AAKIPERARA ILDRWTAPAP EASSPEIPSR AKAFVAELLS 1690 1700 1710 1720 1730 1740 APPSRRRSLV LDRITVETRQ LLGRAAHVRI DPTQSLFELG LDSLSAVQFR TALQRAFGRV 1750 1760 1770 1780 1790 1800 LPASLAFEHP TLDALADALL ALIEADSGTA AAAEPAAAAA ESGNGAIALD AALQGLREGQ 1810 1820 1830 1840 1850 1860 LSLPSLSPSA LATMAETIRT RLPELPVLAA EPIAIVGMGC RFPGGADSPA ELWNLLSNGV 1870 1880 1890 1900 1910 1920 DAITEIPSDR WDRDAWYDPD PDAPDKTPIR HGGFIDDVAE FDAGFFRISP REARCMDPQH 1930 1940 1950 1960 1970 1980 RLLLEVTWQA LEDAGQDPQR LMGTNTGVFI GFMNNDYPSL AELAEFEGHL ATGNGISNAV 1990 2000 2010 2020 2030 2040 GRLSFVLGIH GPSVALDTAC SSSLVAIHSA VESLRKRECN LALAGGVSLI LSPGLTVLMS 2050 2060 2070 2080 2090 2100 KLGGLALDGH CKTFDAAADG YVRSEGCGVL VLKRLSEAQR DRDRIVAVIR GSAVNHGGRS 2110 2120 2130 2140 2150 2160 GGFSQPNARA QQALLREALA RSQTLPHQVS YLEAHGTGTP LGDPIEYRAA AAVYSNGRNT 2170 2180 2190 2200 2210 2220 STPLHIGSIK TNIGHAEAAA GVAGVMKVAL ALQARQIPPH LNLNHLSPEI DLDAVPARIP 2230 2240 2250 2260 2270 2280 TALTPWQPIG GRRIAGVSGF GMSGINAHLV LEEALPSPSQ TDSTQADAVS GEPSSPPRAE 2290 2300 2310 2320 2330 2340 LLALSAQSEA ALLALAEAYQ KHLAEGSTAL PSLHDLAGTA CARRAHHEVR LGLVAGDLPE 2350 2360 2370 2380 2390 2400 VRAGLAAFVR GQTGSRLVTG ACEAGRRPRV VFVCPGQGSQ WLGMGRDLYA NEPAFRDAID 2410 2420 2430 2440 2450 2460 QCERAMQPHA QWRLVERLHA SEPLAGIDVI QPLLFAISVA LGALWRAWGI EPDAVVGHSM 2470 2480 2490 2500 2510 2520 GEVAAAHLAG VLSLDDAARI ICRRSRLMLE VAGRGAMAMV ELGAQQLEPR LARHGDALCV 2530 2540 2550 2560 2570 2580 AASNSTRSSV VTGEAAAIEQ LLAELAAEHV FARRIKVDVA SHGPQVDPLA RPLVECLEGL 2590 2600 2610 2620 2630 2640 RPTAGTIPFW SSVTASLGEG AELGPEYWMR NLRQPVRFAE TITGLLASEH ALFVELSAHP 2650 2660 2670 2680 2690 2700 ILATAIDHTA EDGGSSAWVV GSLERDKPER ATMLRSLAEL YARGYPVDFR RLYPTSASVP 2710 2720 2730 2740 2750 2760 LPTYPFQRQH YWVEQVKTTP LLLRNRPDLV GAAPPIPTHA PIVATAAPWA EWIAELTWQQ 2770 2780 2790 2800 2810 2820 AEPTGTAERG RRYLLFADRG GMAELLAAAL KERGHSCAVL RPEDPAMDGA ALDALADGRP 2830 2840 2850 2860 2870 2880 FHGGIHLGSL DAAATADAGA IPAAEAQAGA IARALTALER YGSPPLWLVT RGGQGIEGEA 2890 2900 2910 2920 2930 2940 PNLSQAAIWG LGRSLAAEHP SLRSALVDLD PALDPTHYPE AAKAGAAHEV AELCRWLTTP 2950 2960 2970 2980 2990 3000 HGEQQLVLRG GHARVARLAR PAEPISSSPA PIHSDRTYWI AGGLAGLGGA VARELVARGA 3010 3020 3030 3040 3050 3060 RHLLVTGGQN ASDVERGGET ARALEAAGAS VVLAGASLTD PEAIASMLKA LSPPLAAVIH 3070 3080 3090 3100 3110 3120 AVPPAAAATA RTVPPSEDAL RSAMTALTDE GWRLYQATRG HALDFVMMFG PAAVLLGGAG 3130 3140 3150 3160 3170 3180 QTAAAVATEV SVALAARWRR EAGPARALLL ASWPGAEEQS LEGVGISAVD VKTVVEAALS 3190 3200 3210 3220 3230 3240 SVTSKTTAAP GQMIASIDWP LFRNVYAQRA DERFFGNLGQ LGREATTASL WRERLRGQPP 3250 3260 3270 3280 3290 3300 EAARKLLHEL VAGEAREVLG LSPEQPLPSR LPFAELGLDS VMALKLMTRL GRALGVRLAT 3310 3320 3330 3340 3350 3360 VLIFEHPTTA ALTEHLANDV LELPPLVAAS DGADSEDDDL SEDELADLLM RKLGSHEGPG

References

[1]

"From Genetic Diversity to Metabolic Unity: Studies on the Biosynthesis of Aurafurones and Aurafuron-like Structures in Myxobacteria and Streptomycetes." Frank B., Wenzel S.C., Bode H.B., Scharfe M., Blocker H., Muller R. J. Mol. Biol. 374:24-38(2007) [PubMed: 17919655] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: DW4/3-1 EMBL CAO98849.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM850130 Genomic DNA. Translation: CAO98849.1.
3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR001227. Ac_transferase_dom. IPR009081. Acyl_carrier_prot-like. IPR014043. Acyl_transferase. IPR016035. Acyl_Trfase/lysoPlipase. IPR000794. Beta-ketoacyl_synthase. IPR018201. Ketoacyl_synth_AS. IPR014031. Ketoacyl_synth_C. IPR014030. Ketoacyl_synth_N. IPR016036. Malonyl_transacylase_ACP-bd. IPR016040. NAD(P)-bd_dom. IPR006163. Phsphopanteth_bd. IPR020842. PKS/FAS_KR. IPR020801. PKS_acyl_transferase. IPR020841. PKS_Beta-ketoAc_synthase_reg. IPR020807. PKS_dehydratase. IPR013968. PKS_KR. IPR020806. PKS_PP-bd. IPR016039. Thiolase-like. IPR016038. Thiolase-like_subgr. [Graphical view]
Gene3D	G3DSA:3.40.366.10. Ac_transferase_reg. 2 hits. G3DSA:3.40.50.720. NAD(P)-bd. 2 hits. G3DSA:3.40.47.10. Thiolase-like_subgr. 4 hits.
PANTHER	PTHR11712. Ketoacyl_synth. 1 hit.
Pfam	PF00698. Acyl_transf_1. 2 hits. PF00109. ketoacyl-synt. 2 hits. PF02801. Ketoacyl-synt_C. 2 hits. PF08659. KR. 2 hits. PF00550. PP-binding. 2 hits. [Graphical view]
SMART	SM00827. PKS_AT. 2 hits. SM00826. PKS_DH. 1 hit. SM00822. PKS_KR. 2 hits. SM00825. PKS_KS. 2 hits. SM00823. PKS_PP. 2 hits. [Graphical view]
SUPFAM	SSF47336. ACP_like. 2 hits. SSF51735. NAD(P)-bd. 2 hits. SSF52151. Acyl_Trfase/lysoPlipase. 2 hits. SSF53901. Thiolase-like. 4 hits. SSF55048. Malonyl_transacylase_ACP-bd. 2 hits.
PROSITE	PS50075. ACP_DOMAIN. 2 hits. PS00606. B_KETOACYL_SYNTHASE. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8YP94_STIAU

Accession

Primary (citable) accession number: A8YP94

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	March 2, 2010
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)