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Protein
Submitted name:

Protein CBR-TWK-1

Gene

twk-1

Organism
Caenorhabditis briggsae
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Protein CBR-TWK-1Imported
Gene namesi
Name:twk-1Imported
Synonyms:Cbr-twk-1Imported
ORF Names:CBG21910Imported, CBG_21910Imported
OrganismiCaenorhabditis briggsaeImported
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008549 Componenti: Chromosome I

Organism-specific databases

WormBaseiCBG21910; CBP31266; WBGene00040580; Cbr-twk-1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei78 – 9922HelicalSequence analysisAdd
BLAST
Transmembranei111 – 13121HelicalSequence analysisAdd
BLAST
Transmembranei137 – 16428HelicalSequence analysisAdd
BLAST
Transmembranei185 – 20925HelicalSequence analysisAdd
BLAST
Transmembranei241 – 26121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliA8Y190.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini86 – 16176Ion_trans_2InterPro annotationAdd
BLAST
Domaini194 – 26875Ion_trans_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000022169.
InParanoidiA8Y190.
OMAiWIHYYGR.
OrthoDBiEOG7GQZ0J.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.

Sequencei

Sequence statusi: Complete.

A8Y190-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFHDEEGGS DKKTIENGRN VEEKDELIEN PIVVKTRKKK RTLPSWLDRP
60 70 80 90 100
YHIWRDQFQQ DKCCPKKRVK QELIRSSIYV LFLNVFLCSY ILFGSNIFTL
110 120 130 140 150
RHTSTEKEAS FLDSVLFCIT TISTIGYGNI VPFDDQGKIL CILYCLIGIP
160 170 180 190 200
LFFMTVATNS MLVLEICNII HRSFSLKEAI NKTDLRWYTS AILLATHCFI
210 220 230 240 250
GSLIFSFWID ELPFLDAFYF SFISITTIGY GDYSPTPEGP FQYAVVMIYL
260 270 280 290 300
CTGVATMLIF FSSLQRGIMW IHYYGRKVSD SEEAEIWYGG QMMTVKDLVS
310 320 330 340 350
LVAQKFGSTP EKLREVMHDL DKILEVACQE AENNEEDDEE AECRRLFMNA
360 370 380 390 400
ESPVSPPMPR KKTVFLSGSS EGDDYQATIH SFTSINQRSI PKETENAIRA
410 420 430 440 450
LGDLQHHLRK PSVRARSPHH SRMIAKPASD TNIEAKEHIT SLDLRKMAHR
460
VHSDGRLLVQ NTV
Length:463
Mass (Da):53,052
Last modified:December 16, 2008 - v2
Checksum:i29D252EF70E7466A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600952 Genomic DNA. Translation: CAP38651.2.

Genome annotation databases

EnsemblMetazoaiCBG21910; CBG21910; CBG21910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600952 Genomic DNA. Translation: CAP38651.2.

3D structure databases

ProteinModelPortaliA8Y190.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCBG21910; CBG21910; CBG21910.

Organism-specific databases

WormBaseiCBG21910; CBP31266; WBGene00040580; Cbr-twk-1.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000022169.
InParanoidiA8Y190.
OMAiWIHYYGR.
OrthoDBiEOG7GQZ0J.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AF16Imported.

Entry informationi

Entry nameiA8Y190_CAEBR
AccessioniPrimary (citable) accession number: A8Y190
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: December 16, 2008
Last modified: May 11, 2016
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.