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Protein
Submitted name:

Protein CBR-TWK-40

Gene

twk-40

Organism
Caenorhabditis briggsae
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Protein CBR-TWK-40Imported
Gene namesi
Name:twk-40Imported
Synonyms:Cbr-twk-40Imported
ORF Names:CBG18237Imported, CBG_18237Imported
OrganismiCaenorhabditis briggsaeImported
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008549 Componenti: Chromosome III

Organism-specific databases

WormBaseiCBG18237a; CBP04292; WBGene00037690; Cbr-twk-40.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 33HelicalSequence analysisAdd BLAST22
Transmembranei115 – 133HelicalSequence analysisAdd BLAST19
Transmembranei145 – 163HelicalSequence analysisAdd BLAST19
Transmembranei216 – 239HelicalSequence analysisAdd BLAST24
Transmembranei246 – 266HelicalSequence analysisAdd BLAST21
Transmembranei272 – 294HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliA8XS78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 170Ion_trans_2InterPro annotationAdd BLAST58
Domaini226 – 297Ion_trans_2InterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000021245.
InParanoidiA8XS78.
KOiK05323.
OMAiWDFFSGF.
OrthoDBiEOG091G05MS.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.

Sequencei

Sequence statusi: Complete.

A8XS78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATWKSYARI ILAHVSLIVL SVVYVGFGAF LFYQLEQPNE VEVRARNIER
60 70 80 90 100
FNIHKRQMID HLWEMRSSGI GQHVVEDMAV KYVDNVTRIL FEAFDTHCIG
110 120 130 140 150
AKHLRPGGED EDYNWTYMTA LFFTTTLLTT IGYGNLTPVT GRGKFLCILY
160 170 180 190 200
ALFGVPLILI TVADIGKFLS ENIVQLYTWY RKLREKCSKQ KYSVISNKDD
210 220 230 240 250
KNKEGDLNLD HLENYISIPI FLIVAILLSY ITFGAVVLSM WEGWDFFSGF
260 270 280 290 300
YFSFITMTTV GFGDIVPLKR EYYILDLCYI IIGLSITTMC IDLVGIQYIR
310 320 330 340 350
KMHYFGRAIK DARFALVNVG GKMVHVPDLM RYASVLQQKY GQKKTHDTII
360 370 380 390
VKGAYAPKDL SKIRFIDFGA LASMESWQSL WSILTGRTQE VHV
Length:393
Mass (Da):45,153
Last modified:January 15, 2008 - v1
Checksum:iD712FC20B54B8B33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600936 Genomic DNA. Translation: CAP35720.1.
RefSeqiXP_002642251.1. XM_002642205.1.

Genome annotation databases

EnsemblMetazoaiCBG18237; CBG18237; CBG18237.
GeneIDi8584246.
KEGGicbr:CBG18237.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600936 Genomic DNA. Translation: CAP35720.1.
RefSeqiXP_002642251.1. XM_002642205.1.

3D structure databases

ProteinModelPortaliA8XS78.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCBG18237; CBG18237; CBG18237.
GeneIDi8584246.
KEGGicbr:CBG18237.

Organism-specific databases

CTDi8584246.
WormBaseiCBG18237a; CBP04292; WBGene00037690; Cbr-twk-40.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000021245.
InParanoidiA8XS78.
KOiK05323.
OMAiWDFFSGF.
OrthoDBiEOG091G05MS.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
ProtoNetiSearch...

Entry informationi

Entry nameiA8XS78_CAEBR
AccessioniPrimary (citable) accession number: A8XS78
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: November 30, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.