A8XLL3 (TPSTB_CAEBR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative protein-tyrosine sulfotransferase
EC=2.8.2.20

Alternative name(s):
Tyrosylprotein sulfotransferase
Short name=TPST

Gene names

Name:	tpst-2
ORF Names:	CBG15241

Organism

Caenorhabditis briggsae

Taxonomic identifier

6238 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	280 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides By similarity. UniProtKB O77081
Catalytic activity	3'-phosphoadenylyl sulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate. UniProtKB O77081
Sequence similarities	Belongs to the protein sulfotransferase family.

Ontologies

Keywords
Molecular function	Transferase
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	protein-tyrosine sulfotransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 280	280	Putative protein-tyrosine sulfotransferase		PRO_0000370219
Amino acid modifications
	Glycosylation	57	1	N-linked (GlcNAc...) Potential
	Glycosylation	136	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	A8XLL3 [UniParc]. Last modified December 16, 2008. Version 2. Checksum: AD0FE2427BBB7D34	FASTA	280	32,285
	10 20 30 40 50 60 MLSNFEQLIF VGGVPRSGTT LMRAILDAHP DVRCGGETML LPSFLTWQAG WRTDWVNNSG 70 80 90 100 110 120 ITQEVFDDAV SAFITEIIAK HGELAPRLCN KDPYTALWLP TIQRLYPNSK FILMIRDARA 130 140 150 160 170 180 VIHSMIERKV PVAGYNTSDE QSMFVKWNQE IRKMLFQCNN APGQCIKVYY ERLIQKPEEE 190 200 210 220 230 240 IQRITNFLDL QYSQQMLHHH ELIGAEVDLN DQEFSASQVK NSINTKALTS WFDCFSEDTL 250 260 270 280 RKLDDVAPFL SVLGYDTSSS KPDYSMFADD DFYQFRNFYS

References

[1]

"The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics." Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N., Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P., Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W., Hillier L.W. , Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A., Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E., Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K., Durbin R.M., Waterston R.H. PLoS Biol. 1:166-192(2003) [PubMed: 14624247] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AF16.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CAAC02000524 Genomic DNA. Translation: CAP33517.2.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
WormBase	CBG15241; CBP27629; WBGene00035555.
Phylogenomic databases
HOGENOM	HBG382344.
Family and domain databases
InterPro	IPR000863. Sulfotransferase_dom. [Graphical view]
Pfam	PF00685. Sulfotransfer_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TPSTB_CAEBR

Accession

Primary (citable) accession number: A8XLL3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	December 16, 2008
Last modified:	September 21, 2011
This is version 21 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Caenorhabditis annotation project